Diabetes & C-Peptide
Scientific and Clinical Aspects
(Sprache: Englisch)
In Diabetes & C-Peptide: Scientific and Clinical Aspects, a renowned group of leading researchers and physicians offers a comprehensive overview of the role of C-Peptide in type 1 diabetes. The book is organized in five sections. An Introductory section...
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In Diabetes & C-Peptide: Scientific and Clinical Aspects, a renowned group of leading researchers and physicians offers a comprehensive overview of the role of C-Peptide in type 1 diabetes. The book is organized in five sections. An Introductory section provides the background and key features of C-peptide's physiological function and how its deficiency contributes to complications. The second section describes up-to-date information on the biochemical and molecular actions of C-peptide, including membrane binding, interactions with insulin as well as the interaction between C-peptide and zinc and effects on microvascular vasoreactivity. The third section summarizes in vivo animal studies of the type 1 diabetic complications. The fourth section reviews the clinical efforts of C-peptide on inflammation, cardiovascular complication, neuropathy and nephropathy. Finally, in the Conclusions section, a summary of the present state of C-peptide, outstanding questions, and the likely direction of the field are offered. Developed by the foremost investigators in the rapidly moving field of C-peptide research, Diabetes & C-Peptide: Scientific and Clinical Aspects is an important contribution to the literature for all researchers and physicians concerned about type 1 diabetes.
Klappentext zu „Diabetes & C-Peptide “
In Diabetes & C-Peptide: Scientific and Clinical Aspects, a renowned group of leading researchers and physicians offers a comprehensive overview of the role of C-Peptide in type 1 diabetes. The book is organized in five sections. An Introductory section provides the background and key features of C-peptide's physiological function and how its deficiency contributes to complications. The second section describes up-to-date information on the biochemical and molecular actions of C-peptide, including membrane binding, interactions with insulin as well as the interaction between C-peptide and zinc and effects on microvascular vasoreactivity. The third section summarizes in vivo animal studies of the type 1 diabetic complications. The fourth section reviews the clinical efforts of C-peptide on inflammation, cardiovascular complication, neuropathy and nephropathy. Finally, in the Conclusions section, a summary of the present state of C-peptide, outstanding questions, and the likely direction of the field are offered. Developed by the foremost investigators in the rapidly moving field of C-peptide research, Diabetes & C-Peptide: Scientific and Clinical Aspects is an important contribution to the literature for all researchers and physicians concerned about type 1 diabetes.
Inhaltsverzeichnis zu „Diabetes & C-Peptide “
PrefaceForewordChapter 1: C-peptide and Insulin - A Happy Marriage Donald. F. Steiner
Chapter 2: Peptide Interactions of Proinsulin C-peptideCharlotte Nerelius, Emma Lindahl, Michael Landreh and Hans Jörnvall
Chapter 3: The Effect of Combined C-peptide and Zinc on Cellular FunctionDana M. Spence
Chapter 4: C-Peptide Signaling in the Kidney and Protection from Diabetic Nephropathy Nigel J. Brunskill
Chapter 5: Role of C-Peptide in the Regulation of Microvascular Blood Flow Thomas Forst, Matthias M. Weber, Thomas Kunt, Andreas Pfützner
Chapter 6: Is NO-eNOS a target for C-peptide action and its protective effects on diabetic nephropathy? Kazuhiro Kimura and Akihiro Kamikawa
Chapter 7: Renoprotective Effects of C-Peptide in Type I DiabetesLina Nordquist, ¿sa Kallas, Sara Stridh, Fredrik Palm, John Wahren
Chapter 8: The Mechanisms Underlying the Effects of C-peptide on Type I Diabetic NeuropathyHideki Kamiya, Wei-Xian Zhang, Anders A.F. Sima
Chapter 9: C-peptide and Type 1 Diabetic EncephalopathyAnders A.F. Sima, Wei-Xian Zhang
Chapter 10: C-peptide: a New Molecule with Anti-Inflammatory PropertiesJaime Haidet, Vincenza Cifarelli, Xuehui Geng, Massimo Trucco, Patrizia Luppi
Chapter 11: C-peptide: Connecting Diabetes with Macrovascular Complications Karen E. Porter, Romana S. Mughal
Chapter 12: C-peptide and Diabetic Neuropathy in Patients with Type I DiabetesKarin Ekberg, John Wahren
Chapter 13: Proatherogenic Effects of C-PeptideDaniel Walcher, Nikolaus Marx
Chapter 14: Conclusions and Future Outlook Anders A.F. Sima
Bibliographische Angaben
- 2012, 184 Seiten, Maße: 18,3 x 26 cm, Gebunden, Englisch
- Herausgegeben: Anders A. F. Sima
- Verlag: Humana Press
- ISBN-10: 1617793906
- ISBN-13: 9781617793905
- Erscheinungsdatum: 03.11.2011
Sprache:
Englisch
Rezension zu „Diabetes & C-Peptide “
From the reviews:"The authors of this volume show in 14 chapters that C-peptide considered and inactive part of proinsulin has a series of metabolic roles. An interesting text. For diabetologists." (Pediatric Endocrinology Reviews (PER), Vol. 9 (3), March, 2012)
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