Dioxin Perspectives

1. Introduction and Background Information.- 1. Participation.- 2. The Pilot Study Organization.- 3. The Nature of the Problem.- References.- 2. Exposure and Hazard Assessment Working Group.- 1. Introduction.- 2. International Exchange of Research and Technology Information on Dioxins and Related Compounds.- 3. Listing of Laboratories with Expertise in the Analysis of Dioxins and Related Compounds.- 4. Inventory of Regulations/Statutes Concerning Dioxins and Related Compounds.- 5. International Toxicity Equivalency Factor (I-TEF) Method of Risk Assessment for Complex Mixtures of Dioxins and Related Compounds.- 6. A Review and Update of Current Knowledge and Methods for Performing Exposure Assessments for 2, 3, 7, 8-TCDD.- 7. Quantitative Implications of the Use of Different Extrapolation Procedures for Low-Dose Cancer Risk Estimates from Exposure to 2, 3, 7, 8-TCDD.- 8. Rationale for a Hormone-Like Mechanism of 2, 3, 7, 8-TCDD for Use in Risk Assessment.- References.- 3. Technology Assessment Working Group.- 1. Introduction to Working Group B Activities.- 2. Formation of Dioxins and Related Compounds from Combustion and Incineration Processes.- 3. Formation of Dioxins and Related Compounds in Industrial Processes.- 4. Methods for Degradation, Destruction, and Detoxification of Dioxins and Related Compounds.- 5. Waste Disposal Sites Contaminated with Dioxins and Related Compounds.- 4. Management of Accidents Working Group.- 1. Introductory Comments on Seveso (Italy) Industrial Accident.- 2. Contingency Planning.- 3. Immediate Emergency Response.- 4. Long-Term Rehabilitation.- 5. Other Contributions.