Energy Transduction in Biological Membranes

Requirement (H+/ATP) for Reversible ATP Synthase
3.10 Storage of Energy in $$ \Delta {\tilde \mu_{{H^{+} }}} $$
3.11 Sufficiency of the Chemiosmotic Framework
3.12 Appendix. Ionophores
3.13 Summary
- Problems

II Components and Pathways for Electron Transport and H+ Translocation
4 Metalloproteins
4.1 Heme Proteins, Cytochromes a through d, and o
4.2 Occurrence of b Cytochromes
4.3 Structure of Cytochrome c
4.4 Structure-Function in Mitochondrial Cytochrome c
4.5 Residues of Reaction Partners That Are Complementary to Cytochrome c Lysines
4.6 Diffusion and Orientability of Cytochrome c
4.7 Membrane-Bound c-Type Cytochromes: Cytochromes c1 and f
4.8 Copper Proteins: Plastocyanin
4.9 Iron-Sulfur Proteins
4.10 Membrane-Bound Iron-Sulfur Proteins
4.11 The Membrane-Bound FeS-Flavoprotein, Succinate: Ubiquinone Oxidoreductase (Complex II)
4.12 Summary
- Problems
5 The Quinone Connection
5.1 Structures, Stoichiometry, Pools, and Branch Points
5.2 Reconstitution of Quinone Function Requires Qn with n ? 3
5.3 The Quinone Pool Is Located Near the Center of the Membrane Bilayer
5.4 The Quinone Connection Across the Center of the Membrane
5.5 Quinone Lateral Mobility
5.6 The Segregation of Electron Transport Components in Thylakoids Requires Lateral Mobility of Quinone
5.7 Quinone-Binding Proteins
5.8 Quinone Electron Acceptors in Photosynthetic Reaction Centers
5.9 Quinone-Binding Proteins in Photosynthetic Reaction Centers
5.10 Summary
- Problems
6 Photosynthesis: Photons to Protons
6.1 Light Energy Transfer
6.2 Use of Energy Transfer as a Spectroscopic Ruler
6.3 Light Energy Transfer in Photosynthesis: The Phycobilisome
6.4 Structures of Photosynthetic Antenna Pigment-Protein Complexes
6.5 Structure of Photosynthetic Reaction Centers
6.6 Structure of the Reaction Center Proteins: Transmembrane Charge Separation
6.7 Reaction Centers of Plant and Algal PS I and II
6.8 Photosynthetic Water Splitting, O2 Evolution, and Proton Release by PS II
6.9 The Cyclic and Noncyclic Electron Transfer Chains
6.10 Summary
- Problems
7 Light and Redox-Linked H+ Translocation: Pumps, Cycles, and Stoichiometry
7.1 Introduction
7.2 Bacteriorhodopsin, a Well-Characterized Light-Driven H+ Pump
7.3 Cytochrome Oxidase (Mitochondrial Complex IV) as a Proton Pump
7.4 The Q Cycle and H+ Translocation in Complex III and Chloroplast b6f Complexes
7.5 H+ Translocation or Deposition Sites in the Mitochondrial, Chromatophore, and Chloroplast Electron Transport Chains; Stoichiometrics of H+ Translocation and ATP Synthesis
7.6 Summary
- Problems

III Utilization of Electrochemical Ion Gradients
8 Transduction of Electrochemical Ion Gradients to ATP Synthesis
8.1 Introduction to the Structure and Function of the ATP Synthase
8.2 Preparation of H+-ATPase
8.3 Structure of F0Fl ATP Synthase
8.4 DNA Sequence of Unc Operon
8.5 Function of the Membrane-Bound Subunits a, b, and c
8.6 Mechanism of ATP Synthesis
8.7 Thermodynamic and Kinetic Constants for ATP Hydrolysis
8.8 Mechanism of Transduction of $$ \Delta {\tilde \mu_{N{a^{+} }}} $$ to ATP
8.9 Other Classes of H+-Translocating ATPases
8.10 Summary
- Problems
9 Active Transport
9.1 Introduction
9.2 Evidence for Protein Carrier-Mediated Transport
9.3 Techniques for Studying Transport in Bacteria
9.4 Structure of the Cell Envelope of Gram-Negative Bacteria
9.5 $$ \Delta {\tilde \mu_{N{a^{+} }}} $$ Formation in Bacteria
9.6 Active Transport of Sugars Coupled to H+ Cotransport
9.7 Kinetic Studies
9.8 Structure/Function Considerations
9.9 Amino Acid Transport
9.10 Sodium-Dependent Transport
9.11 Transport Driven by High-Energy Phosphate Intermediates
9.12 Periplasmic Transport Systems
9.13 Motility
9.14 Active Transport in Eukaryotes
9.15 Transport or Translocation of Macromolecules
9.16 Summary
- Appendix I Answers to Problems
- Appendix II Physical, Chemical, and Biochemical Constants
- Appendix III Prediction of Protein Folding in Membranes
- References
- Glossary of Abbreviations