Essential Biochemistry for Medicine
(Sprache: Englisch)
Dieser kurz gefasste und trotzdem sehr gut lesbare Leitfaden der Biochemie für Mediziner hilft Studienanfängern mit einem unterschiedlichen Niveau der Vorbildung, die biochemischen Grundlagen häufiger Krankheiten zu verstehen. Dazu bindet der Autor die...
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Dieser kurz gefasste und trotzdem sehr gut lesbare Leitfaden der Biochemie für Mediziner hilft Studienanfängern mit einem unterschiedlichen Niveau der Vorbildung, die biochemischen Grundlagen häufiger Krankheiten zu verstehen. Dazu bindet der Autor die Biochemie in die Diskussion klinischer Anwendungen sowie der Diagnose, Ätiologie und Therapie ein. Jedes Kapitel beginnt mit einer kurzen, einfachen Einführung in biochemische Zusammenhänge und Terminologie zur Wiederholung und Orientierung. Der Autor ermutigt die Studenten, den medizinischen Kontext zu betrachten, und fasst gleichzeitig die wichtigsten Eckpunkte der Biochemie für angehende Mediziner zusammen, bevor er zur klinischen Betrachtung überleitet.
Inhaltsverzeichnis zu „Essential Biochemistry for Medicine “
Preface.1 Nutritional requirements.
1.1 Carbohydrates and sugars.
1.2 Glycogen.
1.3 Glycaemic index.
1.4 Lipids.
1.5 Proteins and amino acids.
1.6 Biological value.
1.7 Other energy sources.
1.8 Vitamins.
1.9 Minerals.
2 Metabolism and energy.
2.1 A metabolic strategy.
2.2 Carbohydrate metabolism (catabolic).
2.3 Glycolysis.
2.4 Tricarboxylic acid cycle (TCA cycle - Krebs cycle - citric acid cycle).
2.5 Oxidative phosphorylation.
2.6 Brown adipose tissue and heat generation.
2.7 Glycogenolysis.
2.8 Carbohydrate metabolism (anabolic).
2.9 Gluconeogenesis.
2.10 Glycogenesis.
2.11 Fatty acid catabolism.
2.12 Amino acid catabolism.
2.13 Blood glucose homeostasis.
2.14 Glucokinase and hexokinase.
2.15 Glucose transporters.
2.16 Diabetes mellitus.
2.17 Type 1 diabetes.
2.18 Type 2 diabetes.
2.19 Insulin/Glucagon effects on metabolism.
2.20 Hyperglycaemia and associated pathology.
2.21 Glycation.
2.22 The polyol pathway.
3 Regulating body weight.
3.1 Obesity.
3.2 Weight regulation.
3.3Controlling food intake.
3.4 Pre-gastric factors.
3.5 Gastrointestinal and post-absorptive factors.
3.6 Enteric nervous system.
3.7 The central nervous system.
3.8 Long-term control.
3.9 CNS factors.
3.10 Lifestyle changes.
3.11 The basics of dieting.
3.12 Medical and surgical treatment.
4 Digestion and absorption.
4.1 The gastrointestinal tract.
4.2 Gastric acid production.
4.3 Proton pump inhibitors.
4.4 Helicobacter pylori.
4.5 The small intestine.
4.6 The gastrointestinal barrier.
4.7 Paneth cells.
4.8 The enteric endocrine system.
4.9 The pancreas.
4.10 Absorption in the small intestine: general principles.
4.11 Crossing the gastrointestinal barrier.
4.12 Absorption and secretion of water and electrolytes.
4.13 Pathophysiology of diarrhea.
4.14 Rehydration therapy.
4.15 Absorption of sugars and amino acids.
4.16 Absorption of amino acids and peptides.
4.17 Absorption of lipids.
4.18 Absorption of minerals and metals.
4.19
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Malabsorption syndromes.
4.20 Steatorrhoea.
4.21 Lactose intolerance.
4.22 Glucose-galactose malabsorption.
4.23 Coeliac disease.
4.24 Crohn's disease.
4.25 The large intestine.
5 Synthesis, mobilisation and transport of lipids and lipoproteins.
5.1 Fatty acid synthesis.
5.2 Long-term control of fatty acid synthase.
5.3 Triacylglycerols.
5.4 Mobilisation of lipid stores.
5.5 Transport of lipids.
5.6 Intestinal uptake of lipids.
5.7 Chylomicrons.
5.8 Apolipoproteins.
5.9 Export of fat from the liver.
5.10 Role of HDL in lipid metabolism.
5.11 Apoprotein classes.
5.12 LDL receptors.
5.13 Disorders of lipoprotein metabolism.
5.14 Alzheimer's disease.
5.15 Pharmacologic intervention.
6 Theliver.
6.1 General overview.
6.2 Storage diseases.
6.3 Glycogen storage diseases.
6.4 General liver metabolism.
6.5 Production and excretion of bile.
6.6 Pattern and control of bile secretion.
6.7 Clinical significance of bile secretion.
6.8 Cholesterol metabolism.
6.9 Regulating cholesterol synthesis.
6.10 Regulating sterol synthesis.
6.11 Drug metabolism.
6.12 Breakdown of haem (Haemoglobin).
6.13 Bilirubin.
6.14 Jaundice.
6.15 Protein metabolism - albumin.
6.16 Protein metabolism - nitrogen metabolism and the urea cycle.
6.17 The urea cycle.
6.18 Regulation of the urea cycle.
6.19 Urea cycle defects.
6.20 Neurotoxicity associated with ammonia.
7 Alcohol metabolism and cirrhosis.
7.1 The alcohol dehydrogenase system.
7.2 The microsomal cytochrome P450 system.
7.3 The peroxisome catalase system.
4.20 Steatorrhoea.
4.21 Lactose intolerance.
4.22 Glucose-galactose malabsorption.
4.23 Coeliac disease.
4.24 Crohn's disease.
4.25 The large intestine.
5 Synthesis, mobilisation and transport of lipids and lipoproteins.
5.1 Fatty acid synthesis.
5.2 Long-term control of fatty acid synthase.
5.3 Triacylglycerols.
5.4 Mobilisation of lipid stores.
5.5 Transport of lipids.
5.6 Intestinal uptake of lipids.
5.7 Chylomicrons.
5.8 Apolipoproteins.
5.9 Export of fat from the liver.
5.10 Role of HDL in lipid metabolism.
5.11 Apoprotein classes.
5.12 LDL receptors.
5.13 Disorders of lipoprotein metabolism.
5.14 Alzheimer's disease.
5.15 Pharmacologic intervention.
6 Theliver.
6.1 General overview.
6.2 Storage diseases.
6.3 Glycogen storage diseases.
6.4 General liver metabolism.
6.5 Production and excretion of bile.
6.6 Pattern and control of bile secretion.
6.7 Clinical significance of bile secretion.
6.8 Cholesterol metabolism.
6.9 Regulating cholesterol synthesis.
6.10 Regulating sterol synthesis.
6.11 Drug metabolism.
6.12 Breakdown of haem (Haemoglobin).
6.13 Bilirubin.
6.14 Jaundice.
6.15 Protein metabolism - albumin.
6.16 Protein metabolism - nitrogen metabolism and the urea cycle.
6.17 The urea cycle.
6.18 Regulation of the urea cycle.
6.19 Urea cycle defects.
6.20 Neurotoxicity associated with ammonia.
7 Alcohol metabolism and cirrhosis.
7.1 The alcohol dehydrogenase system.
7.2 The microsomal cytochrome P450 system.
7.3 The peroxisome catalase system.
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Bibliographische Angaben
- Autor: Mitchell Fry
- 2010, 328 Seiten, Maße: 22,9 cm, Gebunden, Englisch
- Verlag: Wiley & Sons
- ISBN-10: 047074328X
- ISBN-13: 9780470743287
Sprache:
Englisch
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