Extrusion-Spheronization VS Solution / Suspension Layering Technique
for Formulation of Itopride Hydrochloride Pellets: A Truce
(Sprache: Englisch)
Purpose: The purpose of this study is to formulate itopride hydrochloride sustained release pellets by Extrusion-Spheronization and Solution/ Suspension layering technique and to compare the pellet characteristics prepared from both the techniques. Methods:...
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Purpose: The purpose of this study is to formulate itopride hydrochloride sustained release pellets by Extrusion-Spheronization and Solution/ Suspension layering technique and to compare the pellet characteristics prepared from both the techniques. Methods: In the Extrusion-Spheronization technique, the drug pellets were prepared by mixing the drug with excipients along with a binder solution, the resultant mass was extruded through extruder followed by spheronizer. In Solution/suspension layering technology the pellets were prepared by coating the drug solution/suspension on the sugar spheres in a fluidized bed processor (FBP). The prepared drug pellets from both the techniques were seal coated with HPMC 5cps followed by sustained release coating of Ethyl cellulose 7cps in the FBP.
Autoren-Porträt von Prateek Kulshrestha
Kulshrestha, PrateekPrateek Kulshrestha has a Masters in Pharmaceutics and done few research projects during his course of study. He now works as a Regulatory Affairs Associate in a leading Life science company.
Bibliographische Angaben
- Autor: Prateek Kulshrestha
- 2018, 104 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 3659635987
- ISBN-13: 9783659635984
Sprache:
Englisch
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