Gemini Surfactant-Based Gene Therapy
Non-invasive gene delivery
(Sprache: Englisch)
Similar to the majority of biological molecules, DNA is degraded rapidly in the body. Its encapsulation into a delivery system increases circulation time and permits accumulation of the drug in certain organs. Lipid-based soft nanoparticles have the ability...
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Similar to the majority of biological molecules, DNA is degraded rapidly in the body. Its encapsulation into a delivery system increases circulation time and permits accumulation of the drug in certain organs. Lipid-based soft nanoparticles have the ability to encapsulate or complex DNA and shuttle it into the cells by overcoming cellular and molecular barriers. The use of state-of-the-art technology for the systematic evaluation of the gene transfer efficiency of the novel nanoparticles leads to the development of in vivo gene delivery systems for topical non-invasive administration. These delivery systems find application in the development of new gene therapy for dermatology, immunology/vaccines and neurodegenerative diseases.
Bibliographische Angaben
- Autoren: Ildiko Badea , Marianna Foldvari
- 2012, Aufl., 240 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 3846581720
- ISBN-13: 9783846581728
Sprache:
Englisch
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