Gene Function Analysis
(Sprache: Englisch)
With the advent of high-throughput technologies following completion of the human genome project and similar projects, the number of genes of interest has expanded and the traditional methods for gene function analysis cannot achieve the throughput...
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With the advent of high-throughput technologies following completion of the human genome project and similar projects, the number of genes of interest has expanded and the traditional methods for gene function analysis cannot achieve the throughput necessary for large-scale exploration. This book brings together a number of recently developed techniques for looking at gene function, including computational, biochemical and biological methods and protocols.
Inhaltsverzeichnis zu „Gene Function Analysis “
Methods in Molecular Biology: Gene Function AnalysisTable of ContentsComputational Methods I1 Gene function inference from gene expression of deletion mutantsGhislain Bidaut2 Association analysis for large scale gene set dataStefan Kirov, Bing Zhang, Jay Snoddy3 Estimating Gene Function with Least Squares Nonnegative MatrixFactorizationGuoli Wang and Michael F. Ochs4 From Promoter Analysis to Transcriptional Regulatory NetworkPrediction Using PAINTGregory E. Gonye, Praveen Chakravarthula, James S. Schwaber,Rajanikanth Vadigepalli5 Prediction of Intrinsic Disorder and its Use in Functional ProteomicsVladimir N. Uversky, Predrag Radivojac, Lilia M. Iakoucheva, ZoranObradovic, A. Keith DunkerComputational Methods II6 Sybil: Methods and Software for Multiple Genome Comparison andVisualizationJonathan Crabtree, Samuel V. Angiuoli, Jennifer R. Wortman, Owen White7 Estimating protein function using protein-protein relationshipsShailesh V. Date8 Bioinformatics tools for modeling transcription factor target genesand epigenetic changesRamana V. Davuluri9 Mining Biomedical Data Using MetaMap Transfer (MMTx) and the UnifiedMedical Language System (UMLS)John D. Osborne, Simon Lin, Lihua (Julie) Zhu, Warren A. Kibbe10 Statistical Methods for Identifying Differentially Expressed GeneCombinationsYen-Yi Ho, Leslie Cope, Marcel Dettling, Giovanni ParmigianiExperimental Methods11 Gene Function Analysis using the chicken B-cell Line DT40Randolph B Caldwell, Petra Fiedler, Ulrike Schoetz and Jean-MarieBuerstedde12 Design and application of an shRNA-based gene replacement retrovirus.Rugang Zhang, Peter D. Adams and Xiaofen Ye13 Construction of simple and efficient DNA vector-based short hairpinRNAexpression systems for specific gene silencing in mammalian cellsTsung-Lin Cheng a and Wen-Tsan Chang14 Selection of recombinant antibodies from antibody gene librariesMichael Hust, Stefan Dübel and Thomas Schirrmann15 A bacterial/yeast merged two-hybrid system: protocol for yeastscreening
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with single or parallel baits.Nadezhda Tikhmyanova, Eugene Izumchenko, Ilya G. Serebriiskii, Erica A.Golemis16 A bacterial/yeast merged two-hybrid system: protocol for bacterialscreeningIlya G. Serebriiskii, Nadia Milech, Erica A. Golemis17 Engineering Cys2His2 Zinc Finger Domains using a BacterialCell-Based Two-Hybrid Selection SystemStacey Thibodeau-Beganny and J. Keith Joung
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Bibliographische Angaben
- 2008, XIV, 337 Seiten, 73 Schwarz-Weiß-Abbildungen, Maße: 15,2 x 23,9 cm, Gebunden, Englisch
- Herausgegeben: Michael Ochs
- Verlag: Springer-Verlag GmbH
- ISBN-10: 1588297349
- ISBN-13: 9781588297341
Sprache:
Englisch
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