Handbook of Green Chemistry - Green Processes

DESIGNING SAFER CHEMICALS The Design of Safer Chemicals: Past, Present, and Future Perspectives Differential Toxicity Characterization of Green Alternative Chemicals Understanding Mechanisms of Metabolic Transformations as a Tool for Designing Safer Chemicals Structural and Toxic Mechanism-Based Approaches to Designing Safer Chemicals Informing Substitution to Safer Alternatives Design of Safer Chemicals - Ionic Liquids Designing Safer Organocatalysts - What Lessons Can Be Learned When the Rebirth of an Old Research Area Coincides with the Advent of Green Chemistry? Life-Cycle Concepts for Sustainable Use of Engineered Nanomaterials in Nanoproducts Drugs Greener Chelating Agents Improvements to the Environmental Performance of Synthetic-Based Drilling Muds Biochemical Pesticides: Green Chemistry Designs by Nature Property-Based Approaches to Design Rules for Reduced Toxicity Reducing Carcinogenicity and Mutagenicity Through Mechanism-Based Molecular Design of Chemicals Reducing Ecotoxicity Designing for Non-Persistence Reducing Physical Hazards: Encouraging Inherently Safer Production Interaction of Chemicals with the Endocrine System

Volume Editors: Prof. Paul T. Anastas, Dr. Bob Boethling and Prof. A. Voutchkova Paul T. Anastas is the Teresa and H. John Heinz III Professor in the Practice of Chemistry for the Environment. He has appointments in the School of Forestry and Environmental Studies, Department of Chemistry, and Department of Chemical Engineering. In addition, Prof. Anastas serves as the Director of the Center for Green Chemistry and Green Engineering at Yale. Anastas took public service leave from Yale to serve as the Assistant Administrator for the US Environmental Protection Agency and the Agency Science Advisor from 2009-2012. From 2004 -2006, Paul Anastas served as Director of the ACS Green Chemistry Institute in Washington, D.C. He was previously the Assistant Director for the Environment in the White House Office of Science and Technology Policy where he worked from 1999-2004. Trained as a synthetic organic chemist, Dr. Anastas received his Ph.D. from Brandeis University and worked as an industrial consultant. He is credited with establishing the field of green chemistry during his time working for the U.S. Environmental Protection Agency as the Chief of the Industrial Chemistry Branch and as the Director of the U.S. Green Chemistry Program. Beside the Handbook of Green Chemistry, Dr. Anastas has published widely on topics of science through sustainability including eleven books, such as Benign by Design, Designing Safer Polymers, Green Engineering, and his seminal work with co-author John Warner, Green Chemistry: Theory and Practice. Dr. Robert (Bob) Boethling is scientist at the U.S. Environmental Protection Agency's Office of Pollution Prevention and Toxics (OPPT), Exposure Assessment Branch. He earned his Ph.D. at UCLA in 1976 and joined EPA in 1980 after a postdoctoral fellowship under Prof. Martin Alexander at Cornell University. Dr. Boethling's expertise is in biodegradation, and design and development of environmental fate data resources and estimation methods. Adelina