Homeostasis - Tumor - Metastasis

Preface
1. Homeostasis
Chemical basis of biological regulation
Definition of homeostasis, allostasis
Aqueous internal environment
Optimal systems
Basic properties of living systems
Metabolism and energy production of living systems
Contribution of biological membranes to homeostasis
Function of the inner environment and its regulated parameters
Cellular, tissue and organ homeostasis
Dimensions of health
Control of processes
Levels of bioregulation
Regulation of multicellular organisms
Major regulatory systems of organisms
Regulatory mechanisms: receptors, reflexes
Maintaining human homeostasis
Evolutionary aspects and types of regeneration
Panic syndromes
References
2. Cell cultures
Cell cultivation
Cell cultures
Establishment of cell cultures
Development of primary tumors
Growth of cell lines
Technical aspects of cell cultivation
Sterile work under the laminar flow hood
Deep freezing, storage of cells
Cell cycle synchronization and its flow cytometric validation
Stem cells
References
3. Loss of homeostasis
Loss of biological balance
Tissue adaptation
Pathological hypertrophies
Heloma
Callus formation
Liver regeneration
References
4. Tumor development
Characterization of benign and malignant tumors
Primary tumor models
Classification of tumors
Tumor tests
Carcinogens
Techniques of tumor screening
Antitumor agents
Benign tumor formation in different tissues and their treatment
General steps in tumor formation
Benign tumors of major organs
References
5. Metastasis
Historical view of metastasis
Spread of tumor cells from local tissue to distant organs
Animal cancer models
Role of parathymic lymph nodes in metastasis
Importance of size distribution of tumor cells in metastasis
Metastasis in different organs
References
Abbreviations