Human Radiation Injury

1: Biology 2: Radiation Pathology Normal Tissue Injury 3: Normal Tissue Radiobiology 4: Fractionation 5: Agents Impacting Radiosensitivity 6: Co-Morbidities 7: Carcinogenesis 8: Atomic Bomb Survivors 9: Optimization of Treatment Delivery 10: Systemic Radiotherapy 11: Effects of Whole Body Exposure 12: Response to Radiologic Terrorism 13: Radiation Effects on Space Travel 14: Nuclear Power Plants 15: Embryo and Fetus 16: Brain Neurocognitive 17: Hypothalamic Pituitary Axis 18: Optic Nerve, Eye and Adnexa 19: Cranial Nerves 20: Brainstem 21: Spine 22: Peripheral Nerve 23: Brachial Plexus 24: Necrosis 25: Vascular Effects 26: Measures to Treat Radiation Injury in the CNS 27: Head and Neck 28: Lung 29: Cardiac 30: Liver 31: Kidney and Adrenal 32: Bladder, Prostate, and Urethra 33: Sexual Function 34: Testes 35: Ovary 36: Vagina 37: Esophagus 38: Small Bowel and Colon 39: Pancreas 40: Stomach 41: Rectum and Anus 42: Breast 43: Bone 44: Skin, Hair, Pigmentation, and Wound Healing 45: Treatment of Late Radiation Injury

"The content of the individual chapters is outstanding." "The references are pertinent and largely comprehensive." "...the electronic version of the book is a magnificent addition that reduces the need for cross-referencing because a reader interested in a particular topic can find all occurrences throughout the text and figures. The electronic format is also a particularly useful tool to aid teaching. Indeed, the figures are usually superb, providing insight beyond that available in the text." "Overall, Human Radiation Injury is an excellent resource and a 'must have' for all practicing radiation oncologists and radiation biologists." Stephen L. Brown, Ph.D. Benjamin Movsas, M.D. Department of Radiation Oncology Henry Ford Hospital and Wayne State University Detroit, MI Human Radiation Injury, edited by Dennis C. Shrieve and Jay S. Loeffler, is a comprehensive textbook of relevant information by a collection of experts. The thoughtful forward written by Samuel Hellman sets the stage by providing a compelling argument for the timely need for this book on radiation injury. The body of the book is divided into four sections. The first section, which describes the basic principles of radiation injury to tissues, includes six chapters, outlining basic radiobiological principles and models, as well as biologics, chemicals, and genetics impacting radiation response. The last chapter, on comorbidities impacting radiosensitivity, is notable for its practicality, although a section describing the optimal timing between radiation and surgery would have been an added benefit. The second section addresses whole-body effects of radiation and provides detailed information covering toxicities due to systemic and total body irradiation, A-bomb survivors' health issues, oncogenesis, response to radiologic and nuclear terrorism, space irradiation, nuclear power plant exposure, and effects on the embryo and fetus. The chapter describing the optimization of radiotherapy delivery to