IKK2
(Sprache: Englisch)
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. IKK- is an enzyme that serves as a protein subunit of I B kinase, which is a component of the cytokine-activated intracellular...
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. IKK- is an enzyme that serves as a protein subunit of I B kinase, which is a component of the cytokine-activated intracellular signaling pathway involved in triggering immune responses. Its activity causes activation of a transcription factor known as Nuclear Transcription factor kappa-B or NF- B. Activated IKK- phosphorylates a protein called the inhibitor of NF- B, I B (I B ), which binds NF- B to inhibit its function. Phosphorylated I B is degraded via the ubiquitination pathway, freeing NF- B, and allowing its entry into the nucleus of the cell where it activates various genes involved in inflammation and other immune responses.
Bibliographische Angaben
- 2010, 153 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Herausgegeben von Surhone, Lambert M.; Tennoe, Mariam T.; Henssonow, Susan F.
- Verlag: Betascript Publishing
- ISBN-10: 613126922X
- ISBN-13: 9786131269226
Sprache:
Englisch
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