Khan: Systematic Reviews to Support Evidence Bsaed Medicine

Khalid S Khan is Professor of Women's Health and Clinical Epidemiology at Barts and the London Medical School in Queen Mary, University of London. He is a clinician, trained in systematic reviews and evidence-based medicine (EBM). Qualified in medical education, he runs journal club and other EBM activities, including evidence-supported ward rounds and workshops on critical appraisal. As a clinical academic he leads a number of systematic review projects, teaches undergraduates and postgraduates, and provides peer review to several clinical journals. Regina Kunz has recently been appointed Director of the Institute for Insurance Medicine at the University and University Hospital Basel, Switzerland. Nephrologist and clinical epidemiologist by training, she has comprehensive expertise in doing systematic reviews, meta-analyses and health technology assessments. Then, her clinical practice reminded her day by day how important it is to have high quality syntheses at hand when advising patients and making management decisions. Today, the lack of high quality evidence synthesis in insurance medicine is a painful experience that urgently needs change. Her academic activities within the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group on guideline methodology and as a long-standing board member of the Guidelines International Network G-I-N corroborate the need for high quality reviews and meta-analyses in all areas of healthcare, to provide physicians, patients and decision makers with sound recommendations, and the difficulties of delivering convincing recommendations in the absence of such reviews. She is the founding member of the German Network EbM, editor of the German textbook Evidence-based Medicine in Clinic and Practice, and has a great deal of experience in running teaching courses on systematic reviews and meta-analyses, the GRADE-methodology and evidence-based medicine worldwide. Jos Kleijnen is the Director of an

"This second edition is justified and timely. Ever since the American Recovery and Reinvestment Act of 2009, there has been great emphasis on comparative effectiveness of evidence-based research such as systematic literature reviews. This well-written, step-by-step guide takes a complex topic and breaks it down into manageable, easy to understand pieces. I would recommend this book for both those new to the field and those who have performed systematic reviews in the past but would like to learn new methods." -- Doody's