Kinomics

PART 1: Protein Kinases Cell Signaling'Genuine' Casein Kinase (Fam20C): The Mother of the Phospho-SecretomeChemical Biology of Protein KinasProtein Kinases and Caspases: Bidirectional Interactions in ApoptosisThe Kinomics of MalariaPART 2: ATP Co-Substrate DesignATP Analogs in Kinase ResearchElectrochemical Detection of Protein Kinase Catalyzed PhosphorylationsPART 3: New Methodologies for KinomicsPhos-tag Technology for KinomicsDevelopment of Species- and Process-Specific Peptide Kinome Arrays with Priority Application to Investigations of Infectious DiseaseNew Approaches to Understanding Bacterial Histidine Kinase Activity and InhibitionMethods for Large-Scale Identification of Protein Kinase-Substrate NetworksPART 4: Kinase InhibitionDeveloping Inhibitors of STAT3: Targeting Downstream of the Kinases for Treating DiseaseMetal Compounds as Kinase and Phosphatase Inhibitors in Drug Development: The Role of the Metal and Ligands

Heinz-Bernhard Kraatz received his Ph.D. from the University of Calgary in 1993. He is a Professor of Chemistry in the Department of Physical and Environmental Sciences and the Department of Chemistry at the University of Toronto. He received a number of awards for his work in biological chemistry. His research is focused on the design surface-supported functional bioconjugates for the study of biological interactions and enzymatic activities including protein kinase catalyzed phosphorylations. His current research interests are in the area of biomaterials and biochemical transformations and analysis.Sanela Martic is an Assistant Professor of Chemistry at Oakland University, USA, since 2012. Dr. Martic received her Ph.D. degree in 2009 from Queen's University at Kingston, under the supervision of Prof. Suning Wang and co-supervision of Prof. Gang Wu. Her Ph.D. dissertation was on the synthesis of fluorescent nucleosides and their self-assembly. Jointly with her colleague, Heinz-Bernhard Kraatz, she focused on the synthesis of the redox active bioconjugates for protein kinase phosphorylations. Her current research interests include the self-assembly of peptides and proteins towards new biomaterials and bioanalytical methods.