Mast Cells

Paul Ehrich's Mastzellen: A Historical Perspective of Relevant Developments in Mast Cell Biology.- The Phylogenetic Profile of Mast Cells.- Mast Cell Development and Function in the Zebrafish.- Human Mast Cell and Basophil/Eosinophil Progenitors.- Methods for the Study of Mast Cell Recruitment and Accumulation in Different Tissues.- Notch2 Signaling in Mast-cell Development & Distribution in the Intestine.- Mast Cells in Human Health and Disease.- The Emerging Prominence of the Cardiac Mast Cell as a Potent Mediator of Adverse Myocardial Remodeling.- The Parasympathetic Nervous System as a Regulator of Mast Cell Function.- Growth of Human Mast Cells from Bone Marrow and Peripheral Blood-Derived CD34+ Pluripotent Hematopoietic Cells.- Isolation and Characterization of Human Intestinal Mast Cells.- Human Mast Cell Activation with Viruses and Pathogen Products.- Basic Techniques to Study FceRI Signaling in Mast Cells.- Membrane-cytoskeleton Dynamics in the Course of Mast Cell Activation.- Fc RI Expression and Dynamics on Mast Cells.- Regulation of Mast Cell Survival and Apoptosis.- Protein Tyrosine Phosphatases in Mast Cell Signaling.- MicroRNA Function in Mast Cell Biology:Protocols to Characterize and Modulate microRNA Expression.- Assay of Mast Cell Mediators.- Induction Of Mast Cell Apoptosis By A Novel Secretory Granule-Mediated Pathway.- Measurement of Nitric Oxide in Mast Cells with the Fluorescent Indicator DAF-FM Diacetate.- Real-time Imaging of Ca2+ Mobilization and Degranulation in Mast Cells.- Flow Cytometry-based Monitoring of Mast Cell Activation.- Measurement of Mast Cell Surface Molecules using High-throughput Immunophenotyping using Transcription (HIT).- Investigatiotion using Novel Mouse Models of Mast Cell Deficiency and Mast Cell-specific Gene Inactivation.- Evaluation of Synovial Mast Cell Functions in Autoimmune Arthritis.- Methods for the Study of Mast Cells in Cancer.- Studying Mast Cells in Peripheral Tolerance byusing a Skin

"Cutting-edge, easily reproducible protocols and methods for the isolation of mast cells and investigation of the molecular mechanisms of their activation and functions can help investigators plan and carry out their experiments. ... aimed primarily at laboratory researchers but also may be useful for all specialists who are interested in mast cell biology. The book is well written, illustrated, summarizes extensive recommendations of world-renowned experts in the field and offers an up-to-date and in-depth look into mast cell biology." (Pavel Kolkhir, World Allergy Organization, WAO Medical Book Reviews, worldallergy.org, July, 2016)