Metabolic Nihilistic Medicine

Human metabolism and climate change leads to human disease and produces the concept of nihilistic medicine. The climate change and global warming/ice age results in endosymbiotic actinidic archaeal growth in the human system and cholesterol catabolism resulting in endogenous digoxin synthesis. The endosymbiotic archaea catabolize cholesterol for its energetics and synthesizes digoxin. Digoxin functions as an endogenous sodium potassium ATPase inhibitor and neuro-immuno-endocrine integrator. The digoxin interference with HERV expression and RNA editing and resultant inhibition of genomic, metabolic, neural and immune diversity produces autoimmune disease, cancer, metabolic syndrome, degenerations, schizophrenia and autism which are increasing at epidemic rates in human population. Digoxin produces alteration in sodium-hydrogen exchange producing an acidic pH and acts like a growth factor producing stem cell transformation of adult cells. Stem cells have a distinct metabolism with increased glycolysis and suppression of PDH and mitochondrial function. This results in neanderthalisation of homo sapiens and human disease resulting in homo sapien extinction.