Micro and Nano Technologies in Bioanalysis

Applications of microfluidics and nanopores in separation, detection, manipulation, and analysis of biomolecules.- HPLC-Chip/MS Technology in Proteomic Profiling.- Nanofluidic Channel Fabrication and Manipulation of DNA Molecules.- A Single-Molecule Barcoding System using Nanoslits for DNA Analysis.- Microfluidic Devices with Photodefinable Pseudo-valves for Protein Separation.- Microfluidic Chips Designed for Measuring Biomolecules Through a Microbead-Based Quantum Dot Fluorescence Assay.- DNA Focusing Using Microfabricated Electrode Arrays.- Solid-State Nanopore for Detecting Individual Biopolymers.- Inserting and Manipulating DNA in a Nanopore with Optical Tweezers.- Forming an ?-Hemolysin Nanopore for Single-Molecule Analysis.- Nanopore Force Spectroscopy on DNA Duplexes.- Technologies of physical science and chemistry in detection and analysis of biomolecules.- Quantitative Chemical Analysis of Single Cells.- Trapping and Detection of Single Molecules in Water.- ZnO Nanorods as an Intracellular Sensor for pH Measurements.- Analysis of Biomolecules Using Surface Plasmons.- Use of Residual Dipolar Couplings in Structural Analysis of Protein-Ligand Complexes by Solution NMR Spectroscopy.- Raman-Assisted X-Ray Crystallography for the Analysis of Biomolecules.- Methods and Software for Diffuse X-Ray Scattering from Protein Crystals.- Deuterium Labeling for Neutron Structure-Function-Dynamics Analysis.- Small-Angle Neutron Scattering for Molecular Biology: Basics and Instrumentation.- Small-Angle Scattering and Neutron Contrast Variation for Studying Bio-Molecular Complexes.- Protein Sequencing with Tandem Mass Spectrometry.- Metabolic Analysis.- Applications of quantum dots and molecular fluorescence in detection, tracking and imaging of biomolecules.- MulticolorDetection of Combed DNA Molecules Using Quantum Dots.- Quantum Dot Molecular Beacons for DNA Detection.- Quantum Dot Hybrid Gel Blotting: A Technique for Identifying Quantum Dot-Protein/Protein-Protein

From the reviews:

"This book provides a comprehensive overview of different modern methods with acknowledged practical interest. ... this book can be considered as unique and highly valuable. ... This book can be recommended for scientists, technicians and students in the fields of molecular and cell biology, biochemistry, microbiology, genetics, medical research and analytical chemistry. ... This book is an excellent source for interested users to learn about recent developments of emerging microtechnologies and nanotechnologies for bioanalysis." (Rosario Pereiro, Analytical and Bioanalytical Chemistry, November, 2009)

"This book describes specific micro and nano techniques used in analyzing functions in both individual cells and animal models. It includes details and tips for using these methods. ... Written for scientists at many different levels, the book includes specific step-by-step instructions in each chapter that would be useful for senior scientists as well as bench technical assistants. ... will be a valuable resource for biomedical scientists." (Rebecca T. Horvat, Doody's Review Service, February, 2010)

From the reviews: "This book provides a comprehensive overview of different modern methods with acknowledged practical interest. ... this book can be considered as unique and highly valuable. ... This book can be recommended for scientists, technicians and students in the fields of molecular and cell biology, biochemistry, microbiology, genetics, medical research and analytical chemistry. ... This book is an excellent source for interested users to learn about recent developments of emerging microtechnologies and nanotechnologies for bioanalysis." (Rosario Pereiro, Analytical and Bioanalytical Chemistry, November, 2009) "This book describes specific micro and nano techniques used in analyzing functions in both individual cells and animal models. It includes details and tips for using these methods. ... Written for scientists at many different levels, the book includes specific step-by-step instructions in each chapter that would be useful for senior scientists as well as bench technical assistants. ... will be a valuable resource for biomedical scientists." (Rebecca T. Horvat, Doody's Review Service, February, 2010)