Microtubule Protocols
(Sprache: Englisch)
This book presents a comprehensive collection of essential and up-to-date methods for studying both the biology of microtubules and the mechanisms of action of microtubule-interacting drugs. The book contains a straightforward presentation of readily...
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Klappentext zu „Microtubule Protocols “
This book presents a comprehensive collection of essential and up-to-date methods for studying both the biology of microtubules and the mechanisms of action of microtubule-interacting drugs. The book contains a straightforward presentation of readily reproducible protocols, tips for troubleshooting, and advice on avoiding common mistakes. Basic scientists and clinical researchers will benefit from this collection.
Inhaltsverzeichnis zu „Microtubule Protocols “
Microtubule Protocols Editor: Zhou, Jun (Nankai University, Tianjin, China) Table of Contents: Chapter 1 (review) Microtubules: an overview Richard H. Wade Chapter 2 Large scale purification of brain tubulin with the modified Weisenberg procedure José Manuel Andreu Chapter 3 Purification and mass-spectrometry identification of microtubule-binding proteins from Xenopus egg extracts Vincent Gache, Patrice Waridel, Sylvie Luche, Andrej Shevchenko and Andrei V. Popov Chapter 4 Preparation and characterization of post-translationally modified tubulins from Artemia Franciscana Paul A. O'Connell and Thomas H. MacRae Chapter 5 Studying the structure of microtubules by electron microscopy Linda A. Amos and Keiko Hirose Chapter 6 Fluorescence microscopy of microtubules in cultured cells Irina Semenova and Vladimir Rodionov Chapter 7 (review) Measurements of stathmin-tubulin interaction in solution Marie-France Carlier Chapter 8 Analysis of microtubule dynamics by polarized light Rudolf Oldenbourg Chapter 9 Visualization of spindle behavior using confocal microscopy Adam I. Marcus Chapter 10 Live cell approaches for studying kinetochore-microtubule interactions in Drosophila Daniel W. Buster and David J. Sharp Chapter 11 Analysis of tubulin transport in nerve processes Andrey Tsvetkov and Sergey Popov Chapter 12 Analysis of microtubule-mediated intracellular viral transport Chunyong Liu, Min Liu and Jun Zhou Chapter 13 Xenopus oocyte wound healing as a model system for analysis of microtubule-actin interactions Tong Zhang and Craig A. Mandato Chapter 14 Screening for inhibitors of microtubule-associated motor proteins Frank Kozielski, Salvatore DeBonis and DimitriosSkoufias Chapter 15 (review) Clinical pharmacology and use of microtubule-targeting agents in cancer therapy Amelia B. Zelnak Chapter 16 Studying drug-tubulin interactions by X-ray crystallography Audrey Dorleans, Marcel Knossow and Benoît Gigant Chapter 17 Characterizing ligand-microtubule binding by competition
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methods José Fernando Díaz and Rubén Martínez Buey Chapter 18 Methods for studying vinca alkaloid interactions with tubulin Sharon Lobert and John J. Correia Chapter 19 High-throughput screening of microtubule-interacting drugs Susan L. Bane, Rudravajhala Ravindra and Anna A. Zaydman Chapter 20 (review) Strategies for the development of novel taxol-like agents Susan L. Mooberry
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Bibliographische Angaben
- 2007, 316 Seiten, Maße: 16 x 24,1 cm, Gebunden, Englisch
- Herausgegeben: Jun Zhou
- Verlag: Humana Press
- ISBN-10: 1588296423
- ISBN-13: 9781588296429
- Erscheinungsdatum: 23.08.2007
Sprache:
Englisch
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