Modeling Fragile X Syndrome
(Sprache: Englisch)
This book offers a comprehensive overview on the molecular basis of fragile X syndrome. It covers all models used to investigate fragile X syndrome and includes state-of-of the art approaches like epigenetics.
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This book offers a comprehensive overview on the molecular basis of fragile X syndrome. It covers all models used to investigate fragile X syndrome and includes state-of-of the art approaches like epigenetics.
Klappentext zu „Modeling Fragile X Syndrome “
Introduction.-Probing Astrocyte Function in Fragile X Syndrome.- Neural Stem Cells.- Fragile X Mental Retardation Protein (FMRP) and the Spinal Sensory System.- The Role of the Postsynaptic Density in the Pathology of the Fragile X Syndrome.- Behavior in a Drosophila model of Fragile X.- Molecular and Genetic Analysis of the Drosophila Model of Fragile X Syndrome.- Fragile X Mental Retardation Protein and Stem Cells.- Manipulating the Fragile X Mental Retardation Proteins in the Frog.- Exploring the Zebra finch Taeniopygia gutta as a Novel Animal Model for the Speech-language Deficit of Fragile X Syndrome.- Neuroendocrine Alterations in the Fragile X Mouse.- Taking STEPs forward to understanding Fragile X Syndrome.- Fmr-1 as an Offspring Genetic and a Maternal Environmental Factor in Neurodevelopmental Disease.- Mouse Models of the Fragile X Premutation and the Fragile X Associated Tremor/Ataxia Syndrome.- Clinical Aspects of the Fragile X Syndrome.- Fragile X Syndrome: A Psychiatric Perspective.- Fragile X Syndrome and Targeted Treatment Trials.- The Fragile X-associate Tremor Ataxia Syndrome.- Vignettes: Models in Absentia.
Inhaltsverzeichnis zu „Modeling Fragile X Syndrome “
Introduction: Reminiscing on Models and Modeling.- Probing Astrocyte Function in Fragile X Syndrome.- Neural Stem Cells.- Fragile X Mental Retardation Protein (FMRP) and the Spinal Sensory System.- The role of the postsynaptic density in the pathology of the fragile X syndrome.- Behavior in a Drosophila model of Fragile X.- Molecular and Genetic Analysis of the Drosophila Model of Fragile X Syndrome.- Fragile X Mental Retardation Protein and Stem Cells.- Manipulating the Fragile Mental Retardation Proteins in the frog.- Exploring the zebra finch Taeniopygia guttata as a novel animal model for the speech-language deficit of fragile X syndrome.- Neuroendocrine alterations in the fragile X mouse.- Taking STEPs forward to understanding Fragile X Syndrome.- Fmr-1 as an offspring genetic and a maternal environmental factor in neurodevelopmental disease.- Mouse Models of the Fragile X Premutation and the Fragile X Associated Tremor/Ataxia Syndrome.- Clinical Aspects of the Fragile X Syndrome.- Fragile X Syndrome: A Psychiatric Perspective.- Fragile X Syndrome and Targeted Treatment Trials.- The Fragile X-associated Tremor Ataxia Syndrome.- Vignettes: Models in Absentia.Bibliographische Angaben
- 2013, 2012, XII, 392 Seiten, Maße: 15,5 x 23,5 cm, Kartoniert (TB), Englisch
- Herausgegeben: Robert B. Denman
- Verlag: Springer, Berlin
- ISBN-10: 3642270107
- ISBN-13: 9783642270109
Sprache:
Englisch
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