Modern Concepts of Focal Epileptic Networks

Modern Concepts of Focal Epileptic Networks Neocortical Focus: Experimental View Malformations of Cortical Development and Neocortical Focus Limbic Networks and Epileptiform Synchronization: The View from the Experimental Side Limbic Networks: Clinical Perspective Modern Concepts of Seizure Modeling Mechanisms of Ictogenesis Seizure Termination Epileptic Focus and Alteration of Metabolism Modern Techniques of Epileptic Focus Localization From Treatment to Cure: Stopping Seizures, Preventing Seizures, and Reducing Brain Propensity to Seize

Dr. Premysl Jiruska is Associate Professor at the Institute of Physiology, Academy of Sciences of Czech Republic. He received his M.D. and Ph.D. degrees from Charles University in Prague Czech Republic. fter completing his PhD, he undertook a postdoctoral position in the group of Prof. John Jefferys at the University of Birmingham, focusing on experimental epilepsy research. In 2008 he was awarded a personal Sir Desmond Pond fellowship by Epilepsy Research UK to conduct independent research on the mechanisms involved in the transition from normal brain activity to seizure. Currently, in his research he focuses on mechanisms of ictogenesis and network organization and dynamics of epileptic foci.Marco de Curtis is Head of the Epilepsy Unit and of the Pre-clinical Neuroscience Laboratories at Fondazione Istituto Neurologico Carlo Besta in Milano, Italy. He is interested in function of neuronal networks in health and disease, with particular focus on epilepsy and ictogenesisJohn G. R. Jefferys was until recently Professor of Neuroscience at the University of Birmingham, moving to the University of Oxford during the final stages of production of this volume. He received his BSc and PhD in Physiology from University College London and is a Fellow of the Academy of Medical Sciences. His research focuses on the emergent properties of neuronal networks and on the fundamental pathophysiology of focal epilepsy.