Molecular Basis of Motility

Welcome.- Hans Hermann Weber in memoriam.- Mechanism of Chemo-mechanical Energy Transformation.- The Structural Basis of Contraction and Regulation in Skeletal Muscle.- An Investigation of the Cross-bridge Cycle Using ATP Analogues and Low-angle X-ray Diffraction from Glycerinated Fibres of Insect Flight Muscle.- The Binding and Cleavage of ATP in the Myosin and Actomyosin ATPase Mechanisms.- The Kinetics of Cross-bridge Turnover.- Energy Transformation in Muscle.- Ca2+ Action and the Regulation of the Actomyosin ATPase.- Release and Uptake of Calcium by the Sarcoplasmic Reticulum.- The Role of the Interaction of Ca2+ with Troponin in the Regulation of Muscle Contraction.- Phosphorylation and the Regulation of the Function of Myosin and the Troponin Complex.- Myosin-linked Calcium Regulation.- Concerted Regulation of Glycogen Metabolism and Muscle Contraction.- Microtubules and Microfilaments.- Microtubules: Inhibition of Spontaneous in vitro Assembly by Non-neural Cell Extracts.- Microfilaments in Blood Platelets.- Studies on the Interaction of the Nerve Growth Factor with Tubulin and Actin.- Phallotoxins and Microfilaments.- Final Comments.