Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development

Histopathology: A Canvas and Landscape of Disease in Drug and Diagnostic Development.- A Field Guide to Homo morphologicus for Biomedical Scientists, Or How to Convey an Understanding of Pathology to Scientists in a Biopharma Enterprise.- Outsourcing Tissue Histopathology Investigations in Support of Clinical Trials for Novel Therapeutics: Considerations and Perspectives.- Histopathology in Mouse Models of Rheumatoid Arthritis.- Markers Used for Visualization and Quantification of Blood Vessels and Lymphatic Vessels.- Practical Approaches to Microvessel Analysis: Hotspots, Microvessel Density, and Vessel Proximity.- Quantitative Histopathology and Alternative Approaches to Assessment of Fibrosis for Drug Development in Hepatitis C and Nonalcoholic Steatohepatitis.- Stereology and Computer-Based Image Analysis Quantifies Heterogeneity and Improves Reproducibility for Grading Reticulin in Myeloproliferative Neoplasms.- Image Analysis Tools for Quantification of Spinal Motor Neuron Subtype Identities.- Development of a Tissue Image Analysis Algorithm for Celiac Drug Development.- Quantitative Histopathology for Evaluation of In Vivo Biocompatibility Associated with Biomedical Implants.- Quantitative Histomorphometry and Quantitative Polymerase Chain Reaction (PCR) as Assessment Tools for Product Development.- Measuring the Messenger: RNA Histology in Formalin Fixed Tissues.- Algorithm-Driven Image Analysis Solutions for RNA ISH Quantification in Human Clinical Tissues.- Solid Tissue-Based DNA Analysis by FISH in Research and Molecular Diagnostics.- Preanalytic Considerations for Molecular Genomic Analyses of Tissue.- Next Generation Sequencing (NGS) in Anatomic Pathology Discovery and Practice.- The Impact of Pre-Analytic Variables on Tissue Quality from Clinical Samples Collected in a Routine Clinical Setting: Implications for Diagnostic Evaluation, Drug Discovery, and Translational Research.- Adapting HER2 Testing for a Different Organ: New Wine in Old Wineskins.-