Mouth Dissolving Tablets: A Novel Approach for Medication
Tramadol Hydrochloride MDT for Management of Pain
(Sprache: Englisch)
Tramadol Hydrochloride (Tramadol HCl) is an opioid analgesic used for treatment of moderate to severe pain. Although its mode of action is not completely understood, at least two complementary mechanisms appear applicable binding to µ-opioid receptors and...
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Tramadol Hydrochloride (Tramadol HCl) is an opioid analgesic used for treatment of moderate to severe pain. Although its mode of action is not completely understood, at least two complementary mechanisms appear applicable binding to µ-opioid receptors and inhibition of re-uptake of nor-adrenaline and serotonin. The drug is available in both oral and parenteral forms, but oral route is more preferred in the form of a tablet. Such type of drug requires rapid onset of action by the achieving immediate release of drug from its dosage form. MDT dissolves or disintegrates quickly in a few seconds in saliva after placing in the oral cavity. In this type of dosage form a portion of medicament is also absorbed through the mouth, pharynx and esophagus as the medicament saliva mixtures descends into the stomach. In this way it provides the rapid onset of action and prevent hepatic first pass metabolism, thus enhancing the bioavaibility of the drug and also enhance the patient compliance.
Autoren-Porträt von Vinod K Dhote, Kanika Dhote
Dhote, Vinod KProf. Vinod K Dhote and Prof. Kanika Dhote having nearly 10 years of academic and research experience in the field of Pharmaceutical sciences. Both possessing research interests in formulation, development of Pharmaceuticals and phyto-pharmaceuticals and having 40 research publications to their credit published internationally and nationally.
Bibliographische Angaben
- Autoren: Vinod K Dhote , Kanika Dhote
- 2020, 92 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 6202522755
- ISBN-13: 9786202522755
Sprache:
Englisch
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