NFYB
(Sprache: Englisch)
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds...
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.
Bibliographische Angaben
- 2010, 108 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Herausgegeben von Surhone, Lambert M.; Tennoe, Mariam T.; Henssonow, Susan F.
- Verlag: Betascript Publishing
- ISBN-10: 6131346720
- ISBN-13: 9786131346729
Sprache:
Englisch
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