Optimal Cancer Screening
Life-Cycle Monte Carlo Simulations for the case of Colon and Rectum Cancers
(Sprache: Englisch)
A dynamic stochastic model for colon and
rectum cancer is developed to obtain the optimal ages
to perform colonoscopies. The currently recommended
guideline for colonoscopy is to test at ages 50, 60,
70, 80 and 90. Our Monte Carlo simulation yields...
rectum cancer is developed to obtain the optimal ages
to perform colonoscopies. The currently recommended
guideline for colonoscopy is to test at ages 50, 60,
70, 80 and 90. Our Monte Carlo simulation yields...
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A dynamic stochastic model for colon and rectum cancer is developed to obtain the optimal ages
to perform colonoscopies. The currently recommended
guideline for colonoscopy is to test at ages 50, 60,
70, 80 and 90. Our Monte Carlo simulation yields a
cost/life-year saved of $54,919.62 for the official
policy. We ask the following: if we could reallocate
the 5 tests between the ages of 50 and 90, which ages
for testing would give the lowest cost/life-year
saved? Of the 91,309 possible policies 43,026, or
47%, have a better cost per life-year saved than the
currently recommended guidelines. The policy with the
lowest cost is to test at the ages of 64, 71, 73, 79,
85 with a cost of $38,081.37 per life-year saved. An
improvement of 30% in the cost/life-year saved. The
framework developed in this paper can be further used
to evaluate the cost effectiveness of current
guidelines for other cancers. The policies can be
personalized by sex and race to have better cost-
effectiveness ratios. Finally, guidelines can be
developed to equate cost per life-year saved across
different cancers.
Autoren-Porträt von Javier Gonzalez
Gonzalez, JavierHe obtained his Ph.D. in economics from the University of Pennsylvania, specializing in computer economics. Previously he received a masters and bachelor in economics from the U. of British Columbia. He has been awarded First Place in the National Mathematics Olympiad and Third Place in the National Physics Olympiad.
Bibliographische Angaben
- Autor: Javier Gonzalez
- 2010, 64 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 3838300890
- ISBN-13: 9783838300894
Sprache:
Englisch
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