Pharmacogenomics in Drug Discovery and Development
(Sprache: Englisch)
The field of pharmacogenomics arose to develop personalized medicine, or medicine that deals with the complexity of the human body. In this book, leading experts present methodical, state-of-the-art contributions covering topics from individual molecules to...
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Produktinformationen zu „Pharmacogenomics in Drug Discovery and Development “
The field of pharmacogenomics arose to develop personalized medicine, or medicine that deals with the complexity of the human body. In this book, leading experts present methodical, state-of-the-art contributions covering topics from individual molecules to systemic diseases, examining both fundamental concepts and advanced technologies. The volume begins by exploring cutting-edge technologies used to pursue systems-based pharmacogenomics, followed by extensive chapters on gene-drug interactions and the use of pharmacogenomics in therapeutics of diseases. This book is ideal for scientists striving to transform disease treatment into disease prevention.
Klappentext zu „Pharmacogenomics in Drug Discovery and Development “
The field of pharmacogenomics arose to develop personalized medicine, or medicine that deals with the complexity of the human body. In this book, leading experts present methodical, state-of-the-art contributions covering topics from individual molecules to systemic diseases, examining both fundamental concepts and advanced technologies. The volume begins by exploring cutting-edge technologies used to pursue systems-based pharmacogenomics, followed by extensive chapters on gene-drug interactions and the use of pharmacogenomics in therapeutics of diseases. This book is ideal for scientists striving to transform disease treatment into disease prevention.
Inhaltsverzeichnis zu „Pharmacogenomics in Drug Discovery and Development “
1. The Integration of Personalized and Systems Medicine: Bioinformatics Support for Pharmacogenomics and Drug Discovery- Qing Yan
2. Applications of Microarrays and Biochips in Pharmacogenomics
- Gary Hardiman
3. Confounding in Genetic Association Studies and Its Solutions
- Donglei Hu and Elad Ziv
4. Pharmacogenetics of Membrane Transporters: A Review of Current Approaches
- Tristan M. Sissung, Erin R. Gardner, Rui Gao, William D. Figg
5. Pharmacogenomics of Drug Metabolizing Enzymes and Drug Transporters in Chemotherapy
- Tessa M. Bosch
6. Pharmacogenomics of G Protein-coupled Receptor Signaling: Insights from Health and Disease
- Miles D. Thompson, David E.C. Cole and Pedro A. Jose
7. G Protein-coupled Receptors Disrupted in Human Genetic Disease
- Miles D. Thompson, Maire E. Percy, W. McIntyre Burnham, and David E.C. Cole
8. G Protein-coupled Receptor Pharmacogenetics
- Miles D. Thompson, Katherine A. Siminoivitch, and David E.C. Cole
9. Epigenetic Alterations of the Dopaminergic System in Major Psychiatric Disorders
- Hamid Mostafavi Abdolmaleky and Sam Thiagalingam
10. Pharmacogenomics in Alzheimer's Disease
- Ramón Cacabelos
11. Pharmacogenetics of Asthma
- Gregory A. Hawkins and Stephen P. Peters
12. From SNPs to Functional Studies in Cardiovascular Pharmacogenomics
- Sharon Cresci
13. Pharmacogenomics in Gastrointestinal Disorders
- Michael Camilleri and Yuri A. Saito
14. Pharmacogenomics in Rheumatoid Arthritis
- Prabha Ranganathan
15. Cancer Pharmacogenetics
- Sharon Marsh
16. Pharmacogenomics in the Preclinical Development of Vaccines: Evaluation of Efficacy and Systemic Toxicity in Mouse Using Array Technology
- Karin J. Regnström
17.Pharmacogenomics in the Evaluation of Efficacy and Adverse Events during Clinical Development of Vaccines
- Lennart J. Nilsson and Karin J. Regnström
Bibliographische Angaben
- 2008, 504 Seiten, Maße: 16 x 24,1 cm, Gebunden, Englisch
- Herausgegeben: Qing Yan
- Verlag: Humana Press
- ISBN-10: 1588298876
- ISBN-13: 9781588298874
- Erscheinungsdatum: 19.03.2008
Sprache:
Englisch
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