Pharmacology and Therapeutics in the New Millennium

Preface. 1. Endothelial Dysfunction and Vascular Disease; P.M. Vanhoutte. 2. Endothelin Receptors: Targets for drug development; A. Ray, et al. 3. Role of Endothelins in Cardiovascular Disease; L.C. Katwa. 4. The Diabetic Vasculature and Endothelin; D.A. Misurski, et al. 5. Beneficial Effects of Renin-Angiotensin System Blockade in Myocardial Infarction; N.S. Dhalla, X. Guo. 6. Role of Angiotensinogen in Human Hypertension; A. Kumar. 7. Biological Function of Cardiac High Molecular Weight Calmodulin-binding Protein; R. Kakkar, et al. 8. A Synthetic Calmodulin-binding Peptide Unmasks Crucial Calmodulin Control of the Calcium-Pumping ATPase in Cardiac Sarcoplasmic Reticulum; N. Narayanan, A. Xu. 9. Pharmacology of Vascular Adenosine Receptors; M.A.H. Talukder, et al. 10. Aquaretic Vasopressin Antagonists to Treat Chronic Hyponatremia; C.N. Corder, et al. 11. Regional Differences in the Regulation of L-type Calcium Current in Heart Cells; R. Kumar, et al. 12. Domoic Acid as a Tool in Molecular Pharmacology; S.K. Sharma, N.S. Dhalla. 13. Molecular Basis of Adapted Heart; D.K. Das, N. Maulik. 14. Gene Therapy and Renin-Angiotensin System; A.S. Pachori, et al. 15. Transgenic and Knockout Mouse Models in New Drug Discovery; V. Kumar. 16. Epidermal Growth Factor Receptor mRNA in Prostate: Clinical Implications and Hormonal Regulation; V.L. Kumar. 17. Angiogenesis: Concepts and Research Methodologies; S. Sengupta, S.K. Gupta. 18. Metabolism-Based Antifolate Drug Design: MDAM and MTREX; A. Amato, et al. 19. Angiogenesis: A New Approach to Glutamine Related Therapy; P. Maity, P. Bhattacharya. 20. Isolation and Characterization of Apoptosis Resistant Mutants: Molecular Targets for Chemoprevention; N. Singh, et al. 21. High Exposure to Caffeine-Derived N-Nitroso Compounds as Carcinogenic Risk for G.I.T. Cancers in Kashmir; M. Siddiqi. 22. Regulation of N-Myristoyl-transferase in Human Colon Cancer; R.V.S. Rajala, et al. 23. Differential Activation and Inhibition of