Principles and Applications of Asymmetric Synthesis
(Sprache: Englisch)
Wer enantiomerenrein oder wenigstens -angereichert synthetisieren will, kommt (insbesondere in der Pharmazie) an der asymmetrischen Synthese kaum vorbei. International angesehene Experten stellten in diesem Band die wichtigsten heute bekannten...
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Wer enantiomerenrein oder wenigstens -angereichert synthetisieren will, kommt (insbesondere in der Pharmazie) an der asymmetrischen Synthese kaum vorbei. International angesehene Experten stellten in diesem Band die wichtigsten heute bekannten stöchiometrischen und katalytischen asymmetrischen Prozesse zusammen. Über 450 Reaktionen werden besprochen - kein anderes Buch zum Thema bietet momentan ein derart breites Spektrum.
Klappentext zu „Principles and Applications of Asymmetric Synthesis “
Convenient reference covering one of the most important topics in chemical research todayPrinciples and Applications of Asymmetric Synthesis
Asymmetric synthesis remains a challenge to practicing scientists as the need for enantiomerically pure or enriched compounds continues to increase. Over the last decade, a large amount of literature has been published in this field. Principles and Applications of Asymmetric Synthesis consolidates and evaluates the most useful methodologies into a one-volume resource for the convenience of practicing scientists and students.
Authored by internationally renowned scientists in the field, this reliable reference covers more than 450 reactions and includes important stoichiometric as well as catalytic asymmetric reactions. The first chapter reviews the basic principles, common nomenclature, and analytical methods, and the remainder of the book is organized according to reaction type. The text examines such topics as:
* Carbon-carbon bond formations involving carbonyls, enamines, imines, and enolates
* Asymmetric C-O bond formations including epoxidation, dihydroxylation, and aminohydroxylation
* Asymmetric synthesis using the Diels-Alder reaction and other cyclizations
* Applications to the total synthesis of natural products
* Use of enzymes in asymmetric synthesis
Practicing chemists in the pharmaceutical, fine chemical, and agricultural professions as well as graduate students will find that Principles and Applications of Asymmetric Synthesis affords comprehensive and current coverage.
Inhaltsverzeichnis zu „Principles and Applications of Asymmetric Synthesis “
Preface.Abbreviations.
Introduction.
-Alkylation and Catalytic Alkylation of Carbonyl Compounds.
Aldol and Related Reactions.
Asymmetric Oxidations.
Asymmetric Diels-Alder and Other Cyclization Reactions.
Asymmetric Catalytic Hydrogenation and Other Reduction Reactions.
Applications of Asymmetric Reactions in the Synthesis of Natural Products.
Enzymatic Reactions and Miscellaneous Asymmetic Syntheses.
Index.
Autoren-Porträt von Guo-Qiang Lin, Li Yue-Ming, Albert S. C. Chan
GUO-QIANG LIN, YUE-MING LI, and ALBERT S. C. CHAN are all professors in the Department of Chemical Technology at The Hong Kong Polytechnic University, Hong Kong, China.
Bibliographische Angaben
- Autoren: Guo-Qiang Lin , Li Yue-Ming , Albert S. C. Chan
- 2001, 1. Auflage, XVIII, 518 Seiten, Maße: 24 cm, Gebunden, Englisch
- Verlag: Wiley & Sons
- ISBN-10: 0471400270
- ISBN-13: 9780471400271
Sprache:
Englisch
Pressezitat
"Lin and colleagues...consolidate and evaluate the most useful methodologies for producing enantiomerically pure or enriched compounds." (SciTech Book News, Vol. 25, No. 3, September 2001)"...a concise and fairly comprehensive overview..." (Angewandte Chemie, 15 October 2001)
"...this book is worthy of purchase for library collections and for chemists who would like to have a one-volume summary of the last 20 years of asymmetric synthesis. Those actively involved in asymmetric synthesis research will find this book most useful..." (Journal of Natural Products, Vol. 64, 2001)
"...a very good review of basic asymmetric methodology that can be recommended to students of organic chemistry..." (Journal of Medicinal Chemistry, Vol. 44, No. 26 2001)
"a well balanced survey of stereocontrolled methodologies and synthetic applications from which the reader can achieve valuable information." (ChemWeb, 14 January 2002)
"This book is quite readable and is highly recommended for those clinicians and administrators who want or need a practical and time-effective way to approach assessment, treatment planning and outcome measurement." (Keith Harris, Ph.D., clinical psychologist and supervisor of Victor Valley Behavioral Health Center, San Bernardino, California).
"There are many books on asymmetric synthesis, but this work...is one of the most useful and comprehensive" (Organic Process Research & Development)
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