Pyridopyrimidines: Synthesis and Biological Activity
Pyridopyrimidines
(Sprache: Englisch)
The original work of the present book consists of three research projects: The first project entitled: Application of Mannich and Michael reactions in synthesis of pyridopyrimido[2,1-b][1,3,5]thiadiazinones and pyridopyrimido[2,1-b][ 1,3] thiazinones as...
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Klappentext zu „Pyridopyrimidines: Synthesis and Biological Activity “
The original work of the present book consists of three research projects: The first project entitled: Application of Mannich and Michael reactions in synthesis of pyridopyrimido[2,1-b][1,3,5]thiadiazinones and pyridopyrimido[2,1-b][ 1,3] thiazinones as anticancer agents.The second project entitled: Synthesis of pyridotriazolopyrimidines as antitumor agents. The third project entitled: Synthesis of Novel Thiadiazole and Pyrazoline Derivatives Bearing pyrido[2,3-d]pyrimidinone Moiety. The mechanism of formation of the synthesized compounds was discussed and the assigned structure was established via microanalysis and spectral data (IR, 1HNMR and Mass). In addition, the antitumor activities of the synthesized compounds were investigated and the results revealed that these compounds exhibited promising activities a gainst HepG-2 and MCF-7 cancer cell lines.
Autoren-Porträt von Sobhi Gomha, Magda A. Abdallah, Mahmoud A. Metwally
Gomha, SobhiProf. Sobhi M. Gomha has been published 170 scientific papers in the fields of synthetic organic chemistry, chemistry of hydrazonoyl halides, chemistry of enaminones, green chemistry and bioactive heterocyclic chemistry (There are about 2500 citations of his work until 15 April 2020 (h-index 29). He supervised 20 M.Sc. and Ph.D. graduate theses.
Bibliographische Angaben
- Autoren: Sobhi Gomha , Magda A. Abdallah , Mahmoud A. Metwally
- 2020, 148 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 6202525290
- ISBN-13: 9786202525299
Sprache:
Englisch
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