Rad50
(Sprache: Englisch)
High Quality Content by WIKIPEDIA articles! RAD50 homolog (S. cerevisiae), also known as RAD50, is a protein which in humans is encoded by the RAD50 gene. The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein...
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High Quality Content by WIKIPEDIA articles! RAD50 homolog (S. cerevisiae), also known as RAD50, is a protein which in humans is encoded by the RAD50 gene. The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Gene knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability.
Bibliographische Angaben
- 2010, 92 Seiten, Kartoniert (TB), Englisch
- Herausgegeben von Surhone, Lambert M.; Timpledon, Miriam T.; Marseken, Susan F.
- Verlag: Betascript Publishing
- ISBN-10: 6131161836
- ISBN-13: 9786131161834
Sprache:
Englisch
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