Radiation Oncology: Radiobiological and Physiological Perspectives
The boundary-zone between clinical radiotherapy and fundamental radiobiology and physiology
(Sprache: Englisch)
During the past four decades knowledge about biological effects of ionizing radiations on mammalian cells, normal tissues and tumours has increased enormously and has enabled radiotherapists to obtain a better insight into the advantages and disadvantages...
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Klappentext zu „Radiation Oncology: Radiobiological and Physiological Perspectives “
During the past four decades knowledge about biological effects of ionizing radiations on mammalian cells, normal tissues and tumours has increased enormously and has enabled radiotherapists to obtain a better insight into the advantages and disadvantages of cancer treatments with modified regimens of irradiations and combinations with chemotherapeutic agents. Even for the older scientists and clinicians who have wit nessed all these developments and have contributed to the vast amount of information, it is difficult to integrate this knowledge and to apply it in their daily work. For younger workers it is often difficult to select the important main concepts and results from the overwhelming number of publications. It is evident that a book which provides an integrated view of basic and applied radiation oncology can be of great value to students, scientists and, most importantly, to clinicians who can devote only part of their time to the task of understanding the radiobiological background of their application of radiation in cancer treatment. This book "Radiation Oncology" is written by a radiotherapist who has for a long time participated in the integration of basic knowledge and clinical experience. He has selected radiobiological information which is considered important to radiotherapy and in the description and interpretation of normal tissue tolerance and tumour eradication probability, he illustrates how basic knowledge can be applied clinically.
Inhaltsverzeichnis zu „Radiation Oncology: Radiobiological and Physiological Perspectives “
I.1 The Overall Radiobiological Effect: the Evolution of Radiation DamageII.1 Dose Survival Relationships: Methodology, Forms, and Interpretations
II.2 Some Modifiers of Dose-response Relationships
II.3 Interaction of Radiation and Chemotherapeutic Agents
III.1 Radiation Effects on Normal Tissues: General Principles
III.2 Dose-time-volume Relationships in Normal Tissue Response to Irradiation
III.3 Early Reacting Tissues: Skin
III.4 Early Reacting Tissues: the Haematopoietic Tissue
III.5 Early Reacting Tissues: the Lymphoid Tissue and the Immune Systems
III.6 Early Reacting Tissues: the Digestive Tract
III.7 Early Reacting Tissues: the Testes
III.8 Radiation Effects on the Ovary: a Nonrenewal System
III.9 Late Reacting Tissues: Radiation-induced Lung Damage
III.10 Late Reacting Tissues: the Urinary Tract
III.11 Late Reacting Normal Tissues: Radiation-induced Liver Damage
III.12 Late Reacting Tissues: Radiation-induced Damage to the Central Nervous System
III.13 Late Reacting Tissues: Radiation-induced Heart Disease
IV.1 Tumour Growth: Organization of Tumour Proliferative Activity
IV.2 Tumour Growth: Patterns, Parameters and Measurement
IV.3 Analysis of the Growth Parameters of Human Tumours: Clinical Implications
IV.4 Tumour Radiation Response: A. Response to a Single Dose
IV.5 Tumour Radiation Response: B. Response to Multifraction and Protracted Low Dose Rate Irradiation
IV.6 Hypoxia in Solid Tumours and Normal Tissues: Clinical Implications
IV.7 Estimates of the Outcome of Radiotherapy. Accuracy requirements
Bibliographische Angaben
- Autor: H. Awwad
- 2012, Softcover reprint of the original 1st ed. 1990, XIV, 682 Seiten, Maße: 15,5 x 23,5 cm, Kartoniert (TB), Englisch
- Verlag: Springer Netherlands
- ISBN-10: 9401578672
- ISBN-13: 9789401578677
Sprache:
Englisch
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