UNI-MED Science / State-of-the-Art Prevention of Adhesions in Gynecology
(Sprache: Englisch)
Intra-abdominal adhesions are a major source for patient morbidity including infertility, chronic pelvic pain and small bowl obstruction. Especially in gynecology, infectious diseases represent the primary cause for adhesions and, in consequence,...
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Klappentext zu „UNI-MED Science / State-of-the-Art Prevention of Adhesions in Gynecology “
Intra-abdominal adhesions are a major source for patient morbidity including infertility, chronic pelvic pain and small bowl obstruction. Especially in gynecology, infectious diseases represent the primary cause for adhesions and, in consequence, infertility.This comprehensive book covers the whole field of adhesions and adhesion related disorders. It will contribute to surgeons becoming more conscious of the adhesions problematic and will give answers on how to treat and how to avoid adhesions. The authors are key opinion leaders in the field of adhesion research and elucidate the problem of adhesions including their pathogenesis, diagnosis and therapy as well as their prognosis.This book provides up-to-date information and is recommended to all operating gynecologists, but also to colleagues of other disciplines such as surgery or urology.
Inhaltsverzeichnis zu „UNI-MED Science / State-of-the-Art Prevention of Adhesions in Gynecology “
1. The Pathogenesis of Adhesion Formation 121.1. Adhesion formation results from abnormal regulation of peritoneal wound healing 121.2. The balance between the formation of a fibrin matrix and fibrinolysis 131.3. The deposition of extracellular matrix material 131.4. Remesothelization, vascularization and innervation of adhesion tissue 131.5. The role of cytokines during the process of adhesion formation 141.6. Conclusion 151.7. References 152. State-of-the-Art in Adhesion Prevention 202.1. Steps to reduce adhesions 202.2. Adhesion-reduction agents 212.2.1. Pharmacological agents 222.2.2. Physical separators 222.2.3. Site-specific mechanical barriers 222.2.4. Gel barriers 252.2.5. Broad-coverage fluid agents 272.2.6. Areas of future research 282.3. Cost-effectiveness of anti-adhesion agents 292.4. Advising patients of adhesions risk and medicolegal considerations 292.5. References 313. Postoperative Adhesions and their Prevention 383.1. Pathophysiology of adhesion formation 393.1.1. The mesothelial cell and the peritoneal cavity 393.1.2. The classic model of adhesion formation: a local phenomenon 403.1.3. The updated model: The peritoneal cavity as a cofactor 413.1.4. Conclusions 413.2. Prevalence and clinical consequences of postoperative adhesion formation 423.3. Prevention of postoperative adhesion formation 433.3.1. Good surgical practice and conditioning of the peritoneal cavity 433.3.2. Adhesion prevention in animal models 443.3.3. Adhesion prevention in humans 453.4. Discussion and outlook 463.5. Summary 473.6. References 484. The Importance and the Timing of Second-Look Laparoscopy 544.1. Pathophysiology 544.2. Prevention of adhesions 564.2.1. Limitation or prevention of initial peritoneal injury 564.2.2. Prevention of coagulation of serous exudates 574.2.3. Removal or dissolution of deposited fibrin 574.2.4. Prevention of adhesions between surfaces of adjacent structures by keeping them apart 574.2.4.1. The barrier technique 574.2.5. Prevention of the
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organisation of the persisting fibrin by means of inhibition of the fibroblast proliferation 584.2.6. Other causes of trauma to the peritoneum 584.3. Conclusions 594.4. References 595. Postoperative Adhesion after Laparoscopic Uterine Reconstructive Surgery 625.1. A brief historical note 625.2. Uterine reconstructive surgery 635.3. Myomectomy 635.4. Uterine adenomyosis 645.5. Uterine wall abnormalities 665.6. Congenital uterine malformations 675.7. Uterine adhesiolysis 675.8. Discussion 695.9. Conclusions 745.10. References 756. Adhesion Prevention in Severe Endometriosis 806.1. Problems caused by adhesions 806.2. Methods for adhesion prevention 816.2.1. Gore-Tex 816.2.2. Interceed 816.2.3. Seprafilm 816.2.4. SprayGel/SprayShield 826.2.5. Adept 826.2.6. Intercoat 826.2.7. Ovariopexy 826.2.8. Second-look laparoscopy 826.3. Adhesion prophylaxis in bowel surgery 836.4. Personal use of adhesion prevention in patients with endometriosis 836.5. Conclusion 836.6. References 847. The Ultimate Challenge - Definition and Standardized Classification of Adhesions 887.1. Classification systems 887.2. Literature 908. ESGE Consensus on the Management of Adhesions 948.1. Actions to reduce adhesions 948.2. Summary 94Index 95
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Bibliographische Angaben
- Autoren: Rudy L. de Wilde , Ernst H. Schmidt
- 2010, 95 Seiten, mit farbigen Abbildungen, Maße: 17,4 x 24,8 cm, Gebunden, Englisch
- Herausgegeben: Rudy Leon De Wilde, Ernst Heinrich Schmidt
- Verlag: UNI-MED, Bremen
- ISBN-10: 3837412458
- ISBN-13: 9783837412451
- Erscheinungsdatum: 01.12.2010
Sprache:
Englisch
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