Synthesis and identification of new derivatives of L-ascorbic acid
(Sprache: Englisch)
In this work, three new derivatives (ligands) of L-ascorbic acid (vitamin C) and their metal complexes have been synthesized and characterized. The first ligand is Bis[O,O-2,3;O,O-5,6-(N,N-dicarboxylicmethylidene)-N-2-methylene pyridyl]-L-ascorbic acid...
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In this work, three new derivatives (ligands) of L-ascorbic acid (vitamin C) and their metal complexes have been synthesized and characterized. The first ligand is Bis[O,O-2,3;O,O-5,6-(N,N-dicarboxylicmethylidene)-N-2-methylene pyridyl]-L-ascorbic acid (LP), was synthesized by the reaction of Bis[O,O-2,3;O,O-5,6-(chloro(carboxylic)methylidene)]-L-ascorbicacid (starting material) with one mmole 2-Picolylamine. The second ligand is Bis[O,O-2,3;O,O-5,6-(thiol(carboxylic)methylidene)]-L-ascorbic acid (LS), was synthesized by the reaction of Bis[O,O-2,3;O,O-5,6-(chloro (carboxylic)methylidene)]-L-ascorbic with excess of sodium sulfide. The third ligand is Bis[O,O-2,3;O,O-5,6-(acetate(carboxylic) methylidene)]-L-ascorbic acid (LA), was performed by the reaction of Bis[O,O-2,3;O,O-5,6-(chloro (carboxylic)methylidene)]-L-ascorbic acid with two mmoles sodium acetate and The biological activities of these ligands LP, LS, LA and some of their complexes which are (Co2+, Cu2+, Cd2+) performedagainst two types of pathogenic bacteria are Staphylococcus aureus (Gram Positive) and Escherichia coli (Gram Negative) in a nutrient agar medium.
Bibliographische Angaben
- Autoren: Fazwi Yahya , Falih H. Musa , Huda A.F. AL-Bayti
- 2016, 184 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: Scholar's Press
- ISBN-10: 3659844411
- ISBN-13: 9783659844416
Sprache:
Englisch
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