Systems Chemical Biology
Integrating Chemistry and Biology Through Cheminformatics Approaches
(Sprache: Englisch)
This book will provide a descriptive outline of both the fundamental and the applied aspects of systems chemical biology approaches, focused primarily on the drug discovery context. It will cover a broad range of aspects related to prediction of phenotypic...
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This book will provide a descriptive outline of both the fundamental and the applied aspects of systems chemical biology approaches, focused primarily on the drug discovery context. It will cover a broad range of aspects related to prediction of phenotypic outcome to interfering with key pathways, as well as the design of small molecule modulators aimed at causing a desired phenotype (or to reverse a given diseased phenotype). These relate to both cellular pathways with the goals of understanding and predicting function, and to strategies in multi-drug targeting. This can also be gauged from the rapid growth in the literature in this direction and the creation of new computational/bioinformatics journals.
The book will also provide an overview, with easy-to-understand chapters written by pioneers and leaders in the field, as well as advanced material, to inform the readers of the potential caveats which might be involved in a particular task at hand. It also clearly highlight the scope of Systems Chemical Biology and includes case studies where computational network models have provided experimental insight.
The book will also provide an overview, with easy-to-understand chapters written by pioneers and leaders in the field, as well as advanced material, to inform the readers of the potential caveats which might be involved in a particular task at hand. It also clearly highlight the scope of Systems Chemical Biology and includes case studies where computational network models have provided experimental insight.
Klappentext zu „Systems Chemical Biology “
This book will provide a descriptive outline of both the fundamental and the applied aspects of systems chemical biology approaches, focused primarily on the drug discovery context. It will cover a broad range of aspects related to prediction of phenotypic outcome to interfering with key pathways, as well as the design of small molecule modulators aimed at causing a desired phenotype (or to reverse a given diseased phenotype). These relate to both cellular pathways with the goals of understanding and predicting function, and to strategies in multi-drug targeting. This can also be gauged from the rapid growth in the literature in this direction and the creation of new computational/bioinformatics journals.The book will also provide an overview, with easy-to-understand chapters written by pioneers and leaders in the field, as well as advanced material, to inform the readers of the potential caveats which might be involved in a particular task at hand. It also clearly highlight the scope of Systems Chemical Biology and includes case studies where computational network models have provided experimental insight.
Autoren-Porträt von Andreas Bender, Rajarshi Guha, Josef Scheiber
PD. Dr. med. Andreas Bender, Neurologische Klinik, Klinikum der Universität München. Der Autor engagiert sich seit langem in der Lehre und sieht es als persönliche Herausforderung an, seinen Studenten nicht nur neurologisches Faktenwissen, sondern auch Spaß am spannenden Fach Neurologie zu vermitteln.
Bibliographische Angaben
- Autoren: Andreas Bender , Rajarshi Guha , Josef Scheiber
- 2018, 1st ed., 300 Seiten, Maße: 25 cm, Gebunden, Englisch
- Verlag: Wiley & Sons
- ISBN-10: 0470554479
- ISBN-13: 9780470554470
- Erscheinungsdatum: 17.05.2018
Sprache:
Englisch
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