The Molecular Immunology of Complex Carbohydrates-3

Introduction to Glyco-Experiences.Serendipity in Scientific Discoveries: Some Examples in Glycosciences.My 30 Years Devotion to the N-linked Oligosaccharide Structures.- Blood group ABH/Le-related antigens.Human Blood Group ABH/Ii, Lea, b, x, y and Sialyl Lea, x Glycotopes, Internal Structures and Immunochemical Roles of Human Ovarian Cyst Glycoproteins.Lewis Glyco-Epitopes: Structure, Biosynthesis and Functions.An Unique Endo- -Galactosidase that Cleaves Both Blood Group A and B Glycotopes.- Lectins.Recognition Intensities of Mammalian Structural Units, Ligand Clusters and Polyvalency in the Lectin-Glycan Interaction Processes.Adhesion/Growth-Regulatory Galectins: Insights into their Ligand Selectivity Using Natural Glycoproteins and Glycotopes.Glycotope Structures and Intramolecular Affinity Factors of Plant Lectins for Tn/T Antigens.The Five Bacterial Lectins (PA-IL, PA-IIL, RSL, RS-IIL and CV-IIL) - Interactions with Diverse Animal Cells and Glycoproteins.On the Differential Sialic Acid Specificity of Lectins from Different Parts of Saraca indica.Regulation of Lectin Production by the Human Pathogens Pseudomonas aeruginosa and Chromobacterium violaceum: Effects of Choline, Trehalose and Ethanol.Non-Carbohydrate Mediated Interaction of Lectins with Plant Proteins.Novel Concepts about the Role of Lectins in the Plant Cell.- Structures and Functions of Glycolipids.Role of Gangliosides and of Plasma Membrane Associated Sialidase in the Process of Cell Membrane Organization.9-O-Acetyl GD3 in Lymphoid and Erythroid Cells.GM3 Up-Regulation of Matrix Metalloproteinase-9 (MMP-9) Possibly through PI3K, AKT, RICTOR, RhoGDI-2 and TNF- Pathways in Mouse Melanoma B16 Cells.Pathological Roles of Ganglioside Mimicry in Guillain-Barré Syndrome and Related Neuropathies.Structure and Function of Glycolipids in Thermophilic Bacteria.Lipooligosaccharides (LOSs) of Neisseria Species: Similarity between N. Polysaccharea and N. Meningitidis LOSs.- Structures andFunctions of Complex

Dr. Wu has been studying on lectin-glycan interactions for more than 35 years, especially the recognition factors of lectins. He is the senior editor of the Molecular Immunology of Complex Carbohydrates 1 and 2 (Adv. Exp. Med. Biol. 228 and 491). Lectin recognition index is his ongoing project.