Therapeutic Advances in Thrombosis

Contributors, viiForeword, xPreface, xi1 Arterial thrombosis: a brief overview, 1Lina Badimon and Valentin Fuster2 Aspirin, 12Carlo Patrono3 Platelet ADP P2Y12 inhibitors: thienopyridines, 26Joseph D. Foley III and David J. Moliterno4 Platelet ADP P2Y12 inhibitors: nonthienopyridines, 47Joseph D. Foley III and David J. Moliterno5 Cilostazol and dipyridamole: more than weak inhibition of platelets, 62Wolfgang G. Eisert6 Interrelationship of thrombin and platelets: the protease activated receptor-1, 71Matthew E. Wiisanen and David J. Moliterno7 Glycoprotein IIb/IIIa inhibitors, 87Marco Valgimigli and Elisa Cangiano8 Unfractionated heparin and low molecular weight heparin in ischemic heart disease, 111Zafar Iqbal, Omar Hasan, and Marc Cohen9 Pentasaccharide derivatives, 128Antonio Gutierrez, Pierluigi Tricoci, and John H.P. Alexander10 Intravenous direct thrombin inhibitors, 150Femi Philip and A. Michael Lincoff11 Vitamin K antagonists, 166Freek W.A. Verheugt12 Oral direct thrombin inhibitors and oral factor Xa inhibitors, 180Steen Husted and Lars Wallentin13 Thrombolytic therapy and concomitant antithrombotic therapies, 189Peter R. Sinnaeve and Frans J. Van de Werf14 Antithrombotic therapy in ST-segment elevation myocardial infarction, 205Kurt Huber, Raffaele De Caterina, and Steen Dalby Kristensen15 Antithrombotic therapy in non-ST-segment elevation acute coronary syndromes, 213Georgios J. Vlachojannis, Vijayalakshmi Kunadian, Joseph M. Sweeny, and Roxana Mehran16 Antithrombotic strategies in patients undergoing elective percutaneous coronary intervention, 236Sunil V. Rao and E. Magnus Ohman17 Antithrombotic management in patients with prosthetic valves, 246Eric G. Butchart and Raffaele De Caterina18 Stroke: thrombolysis and antithrombotic therapy, 272L. Creed Pettigrew and Michael R. Dobbs19 Atrial fibrillation: current and forthcoming antithrombotic therapies, 285Raffaele De Caterina and Giulia Renda20 Venous thromboembolism: pathophysiology, diagnosis, and