Tumor-Induced Immune Suppression
Mechanisms and Therapeutic Reversal
(Sprache: Englisch)
This monograph, for the first time, presents a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It discusses new mechanisms that have never been discussed in a monograph before.
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Produktinformationen zu „Tumor-Induced Immune Suppression “
This monograph, for the first time, presents a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It discusses new mechanisms that have never been discussed in a monograph before.
Klappentext zu „Tumor-Induced Immune Suppression “
This monograph, for the first time, presents a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It discusses a number of new mechanisms that have never been discussed in a monograph before: T-cell inhibitory molecules, regulatory tolerogenic DCs, and signaling pathways in antigen-presenting cells involved in T-cell tolerance. There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in a more or less cohesive structure and how they can help to improve immune response to tumors.
Inhaltsverzeichnis zu „Tumor-Induced Immune Suppression “
Immune-Suppressive Mechanisms and Cancer: Understanding the Implications, Paradoxes, and Burning Questions.- Mechanisms of Tumor-Associated T-Cell Tolerance.- Contribution of B7-H1/PD-1 Co-inhibitory Pathway to T-Cell Dysfunction in Cancer.- Regulatory T Cells in Cancer.- Cancer-Induced Signaling Defects in Antitumor T Cells.- Immunobiology of Dendritic Cells in Cancer.- Macrophages and Tumor Development.- Myeloid-Derived Suppressor Cells in Cancer.- Signaling Pathways in Antigen-Presenting Cells Involved in the Induction of Antigen-Specific T-Cell Tolerance.- Arginine Availability Regulates T-Cell Function in Cancer.- Protein-Glycan Interactions in the Regulation of Immune Cell Function in Cancer: Lessons from the Study of Galectins-1 and -3.- Role of Reactive Oxygen Species in T-Cell Defects in Cancer.- Tumor Stroma and the Antitumor Immune Response.
Bibliographische Angaben
- 2010, 2008., 302 Seiten, Maße: 23,5 cm, Kartoniert (TB), Englisch
- Herausgegeben:Gabrilovich, Dmitry I.; Hurwitz, Arthur Andrew
- Verlag: Springer, New York
- ISBN-10: 1441924000
- ISBN-13: 9781441924001
Sprache:
Englisch
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