Valaciclovir
(Sprache: Englisch)
High Quality Content by WIKIPEDIA articles! Valaciclovir (INN) or valacyclovir (USAN) is an antiviral drug used in the management of herpes simplex and herpes zoster (shingles). It is a prodrug, being converted in vivo to aciclovir. It is marketed by...
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High Quality Content by WIKIPEDIA articles! Valaciclovir (INN) or valacyclovir (USAN) is an antiviral drug used in the management of herpes simplex and herpes zoster (shingles). It is a prodrug, being converted in vivo to aciclovir. It is marketed by GlaxoSmithKline under the trade name Valtrex or Zelitrex. As of November 25, 2009 (2009 -11-25), Valacyclovir is being marketed in generic form in the United States by Ranbaxy Laboratories. Valaciclovir is a prodrug, an esterified version of aciclovir that has greater oral bioavailability (about 55%) than aciclovir (10-20%). It is converted by esterases to the active drug aciclovir, as well as the amino acid valine, via hepatic first-pass metabolism.
Bibliographische Angaben
- 2010, 100 Seiten, Maße: 15 x 22 cm, Kartoniert (TB), Englisch
- Herausgegeben von Surhone, Lambert M.; Timpledon, Miriam T.; Marseken, Susan F.
- Verlag: Betascript Publishing
- ISBN-10: 6131142017
- ISBN-13: 9786131142017
Sprache:
Englisch
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