Animal Models for the Study of Human Disease (ePub)

P. Michael Conn is the Senior Vice President for Research and Associate Provost, Texas Tech Health Sciences Center. He is The Robert C. Kimbrough, Professor of Internal Medicine and Cell Biology/Biochemistry. He was previously Director of Research Advocacy and Professor of Physiology and Pharmacology, Cell Biology and Development and Obstetrics and Gynecology at Oregon Health and Science University and Senior Scientist of the Oregon National Primate Research Center (ONPRC). He served for twelve years as Special Assistant to the President and Associate Director of the ONPRC. After receiving a B.S. degree and teaching certification from the University of Michigan (1971), a M.S. from North Carolina State University (1973), and a Ph.D. degree from Baylor College of Medicine (1976), Conn did a fellowship at the NIH, then joined the faculty in the Department of Pharmacology, Duke University Medical Center where he was promoted to Associate Professor in 1982. In 1984, he became Professor and Head of Pharmacology at the University of Iowa College of Medicine, a position he held for eleven years. Conn is known for his research in the area of the cellular and molecular basis of action of gonadotropin releasing hormone action in the pituitary and therapeutic approaches that restore misfolded proteins to function. His work has led to drugs that have benefitted humans and animals. Most recently, he has identified a new class of drugs, pharmacoperones, which act by regulating the intracellular trafficking of receptors, enzymes and ion channels. He has authored or co-authored over 350 publications in this area and written or edited over 200 books, including texts in neurosciences, molecular biology and endocrinology. Conn has served as the editor of many professional journals and book series (Endocrinology, Journal of Clinical Endocrinology and Metabolism, Endocrine, Methods, Progress in Molecular Biology and Translational Science and Contemporary Endocrinology). Conn served on

Dieses eBook können Sie uneingeschränkt auf allen Geräten der tolino Familie lesen. Zum Lesen auf sonstigen eReadern und am PC benötigen Sie eine Adobe ID.

"...addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine."--Anticancer Research, February 2015

"…a very detailed textbook for researchers and laboratory animal veterinarians interested in getting an understanding of some of the animal models of human diseases. The authors have done a good job of reviewing the numerous animal models in various physiological systems."--Laboratory Animal Practitioner, June 2014

"Conn presents this compendium on animal models in biomedical research, beginning with a section on ethical justifications, resources, and methodology to optimize the scientific value obtained from animal experiments. After this discussion, the volume is organized by disease group…The book aims to present successful animal models with the greatest homology to human systems."--ProtoView.com, February 2014

"This comprehensive textbook identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease…Organized by disease orientation for ease of searchability…Provides information on locating resources, animal alternatives and animal ethics."--Anticancer Research, 34, 2014

"…overall, the content (figures, tables and descriptions of the animal models and their significance) is excellent and should be considered a useful resource…Any laboratory animal research program, particularly those with an interest in working with multiple species of animal models, would benefit from having this book in the library."--Lab Animal, February 2014