Current and Future Issues in Hemophilia Care (PDF)

List of Contributors. Preface. Part 1: INTRODUCTION. 1 History of Hemophilia (Caroline Cromwell and Louis Aledort). 2 Hemophilia Care in the Modern World (Christine A. Lee). 3 Comprehensive Care Model in Hemophilia (Prasad Mathew). Part 2: GENERAL TOPICS. 4 When Should We Switch From On-Demand to Prophylaxis Regimen? (José A. Aznar, Andres Moret, Lydia Abad-Franch, Ana Rosa Cid, Saturnino Haya and Felipe Querol). 5 Prophylaxis in Children (M. Manco-Johnson). 6 Prophylaxis in Adults with Hemophilia (Victor Jiménez -Yuste, Emérito-Carlos Rodríguez-Merchán, Maria-Teresa Alvarez-Román, Monica Martín -Salces). 7 The Economics of Prophylaxis: Does Prophylaxis with Clotting Factor Represent Value for Money? (Alec Miners). 8 The Transition of Care for the Young Adult Hemophilia Patient (Pia Petrini). 9 Perinatal Clinical Care and Molecular Diagnosis in Hemophilia (Carmen Altisent and Francisco Vidal). 10 Managing the Mature Person with Hemophilia (Savita Rangarajan and Thynn Thynn Yee). 11 Quality of Life in Hemophilia (Eduardo Remor). Part 3: INHIBITORS. 12 Immunology of Inhibitor Development (Birgit M Reipert, Christoph J Hofbauer, Katharina N Steinitz, Hans-Peter Schwarz, FM Horling). 13 Epidemiology of Inhibitors (Johanna G. Van der Bom) 14 Early Tolerisation to Minimise Inhibitors in PUPS with Hemophilia A (Günter Auerswald and Karin Kurnik). 15 Prediction of Inhibitors in Severe Hemophilia (H. Marijke van den Berg and Kathelijn Fischer). 16 Genetic basis for Inhibitor Development (Johannes Oldenburg and Anna Pavlova). 17 Non-Genetic Risk Factors for Inhibitor Development (Lisa N. Boggio and Mindy L. Simpson). Part 4: INHIBITOR TREATMENT. 18 Immune Tolerance Induction Programmes (Jan Blatny and Prasad Mathew). 19 Prophylaxis in Hemophilia A Patients with Inhibitors (Leonard A. Valentino and Guy Young). 20 Treatment of Bleeding in FVIII Inhibitor Patients (Paul Giangrande and Jerome Teitel). 21 Discordancy of By-Passing Therapy (Jan Astermark). Part 5: JOINT HEALTH AND

E. C. Rodriguez-Merchan, MD, PhD, Consultant Orthopaedic Surgeon, Service of Traumatology and Orthopaedic Surgery, Haemophilia Centre, La Paz University Hospital, Madrid, Spain.

Dr Rodriguez-Merchan is a leading orthopaedic surgeon specialising in the treatment of haemophilia. He has 127 articles on PubMed.

Leonard A. Valentino, MD, Professor of Pediatrics; Director, Rush Hemophilia and Thrombophilia Center; Past-President, Hemophilia and Thrombosis Research Society, Rush University Medical Center, Chicago, USA.
Dr Valentino is a paediatrician specialising in haematology and oncology. He has 60 articles on PubMed.

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