Genetic Analysis of Complex Disease (PDF)
(Sprache: Englisch)
Second Edition features the latest tools for uncovering thegenetic basis of human disease
The Second Edition of this landmark publication bringstogether a team of leading experts in the field to thoroughlyupdate the publication. Readers will discover the...
The Second Edition of this landmark publication bringstogether a team of leading experts in the field to thoroughlyupdate the publication. Readers will discover the...
sofort als Download lieferbar
eBook (pdf)
117.99 €
- Lastschrift, Kreditkarte, Paypal, Rechnung
- Kostenloser tolino webreader
Produktdetails
Produktinformationen zu „Genetic Analysis of Complex Disease (PDF)“
Second Edition features the latest tools for uncovering thegenetic basis of human disease
The Second Edition of this landmark publication bringstogether a team of leading experts in the field to thoroughlyupdate the publication. Readers will discover the tremendousadvances made in human genetics in the seven years that haveelapsed since the First Edition. Once again, the editorshave assembled a comprehensive introduction to the strategies,designs, and methods of analysis for the discovery of genes incommon and genetically complex traits. The growing social, legal,and ethical issues surrounding the field are thoroughly examined aswell.
Rather than focusing on technical details or particularmethodologies, the editors take a broader approach that emphasizesconcepts and experimental design. Readers familiar with theFirst Edition will find new and cutting-edge materialincorporated into the text:
* Updated presentations of bioinformatics, multiple comparisons,sample size requirements, parametric linkage analysis, case-controland family-based approaches, and genomic screening
* New methods for analysis of gene-gene and gene-environmentinteractions
* A completely rewritten and updated chapter on determininggenetic components of disease
* New chapters covering molecular genomic approaches such asmicroarray and SAGE analyses using single nucleotide polymorphism(SNP) and cDNA expression data, as well as quantitative trait loci(QTL) mapping
The editors, two of the world's leading genetic epidemiologists,have ensured that each chapter adheres to a consistent and highstandard. Each one includes all-new discussion questions andpractical examples. Chapter summaries highlight key points, and alist of references for each chapter opens the door to furtherinvestigation of specific topics.
Molecular biologists, human geneticists, geneticepidemiologists, and clinical and pharmaceutical researchers willfind the Second Edition a helpful guide to understanding thegenetic basis of human disease, with its new tools for detectingrisk factors and discovering treatment strategies.
The Second Edition of this landmark publication bringstogether a team of leading experts in the field to thoroughlyupdate the publication. Readers will discover the tremendousadvances made in human genetics in the seven years that haveelapsed since the First Edition. Once again, the editorshave assembled a comprehensive introduction to the strategies,designs, and methods of analysis for the discovery of genes incommon and genetically complex traits. The growing social, legal,and ethical issues surrounding the field are thoroughly examined aswell.
Rather than focusing on technical details or particularmethodologies, the editors take a broader approach that emphasizesconcepts and experimental design. Readers familiar with theFirst Edition will find new and cutting-edge materialincorporated into the text:
* Updated presentations of bioinformatics, multiple comparisons,sample size requirements, parametric linkage analysis, case-controland family-based approaches, and genomic screening
* New methods for analysis of gene-gene and gene-environmentinteractions
* A completely rewritten and updated chapter on determininggenetic components of disease
* New chapters covering molecular genomic approaches such asmicroarray and SAGE analyses using single nucleotide polymorphism(SNP) and cDNA expression data, as well as quantitative trait loci(QTL) mapping
The editors, two of the world's leading genetic epidemiologists,have ensured that each chapter adheres to a consistent and highstandard. Each one includes all-new discussion questions andpractical examples. Chapter summaries highlight key points, and alist of references for each chapter opens the door to furtherinvestigation of specific topics.
Molecular biologists, human geneticists, geneticepidemiologists, and clinical and pharmaceutical researchers willfind the Second Edition a helpful guide to understanding thegenetic basis of human disease, with its new tools for detectingrisk factors and discovering treatment strategies.
Autoren-Porträt von Jonathan L. Haines, Margaret A. Pericak-Vance
JONATHAN L. HAINES is Director of the Program in HumanGenetics, Department of Molecular Physiology and Biophysics,Vanderbilt University School of Medicine. His research into thelocalization and identification of genes involved in human diseaseincludes studying Alzheimer's disease, multiple sclerosis,Parkinson's disease, autism, macular degeneration, and othercomplex diseases.MARGARET A. PERICAK-VANCE is Director of the Center forHuman Genetics and Chief of the Section of Medical Genetics in theDepartment of Medicine, Duke University School of Medicine. She isa founding Fellow of the American College of Medical Genetics. Herresearch interests include the integration of genomic andstatistical technologies and their application to diseases ofimportance to public health, with an emphasis on neurologicdiseases.
Bibliographische Angaben
- Autoren: Jonathan L. Haines , Margaret A. Pericak-Vance
- 2007, 2. Auflage, 512 Seiten, Englisch
- Verlag: John Wiley & Sons
- ISBN-10: 0471781134
- ISBN-13: 9780471781134
- Erscheinungsdatum: 30.08.2007
Abhängig von Bildschirmgröße und eingestellter Schriftgröße kann die Seitenzahl auf Ihrem Lesegerät variieren.
eBook Informationen
- Dateiformat: PDF
- Größe: 3.54 MB
- Mit Kopierschutz
Sprache:
Englisch
Kopierschutz
Dieses eBook können Sie uneingeschränkt auf allen Geräten der tolino Familie lesen. Zum Lesen auf sonstigen eReadern und am PC benötigen Sie eine Adobe ID.
Kommentar zu "Genetic Analysis of Complex Disease"
0 Gebrauchte Artikel zu „Genetic Analysis of Complex Disease“
Zustand | Preis | Porto | Zahlung | Verkäufer | Rating |
---|
Schreiben Sie einen Kommentar zu "Genetic Analysis of Complex Disease".
Kommentar verfassen