HPLC for Pharmaceutical Scientists (PDF)
(Sprache: Englisch)
HPLC for Pharmaceutical Scientists is an excellent book for
both novice and experienced pharmaceutical chemists who regularly
use HPLC as an analytical tool to solve challenging problems in the
pharmaceutical industry. It provides a unified approach to...
both novice and experienced pharmaceutical chemists who regularly
use HPLC as an analytical tool to solve challenging problems in the
pharmaceutical industry. It provides a unified approach to...
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HPLC for Pharmaceutical Scientists is an excellent book for
both novice and experienced pharmaceutical chemists who regularly
use HPLC as an analytical tool to solve challenging problems in the
pharmaceutical industry. It provides a unified approach to HPLC
with an equal and balanced treatment of the theory and practice of
HPLC in the pharmaceutical industry.
In-depth discussion of retention processes, modern HPLC
separation theory, properties of stationary phases and columns are
well blended with the practical aspects of fast and effective
method development and method validation. Practical and pragmatic
approaches and actual examples of effective development of
selective and rugged HPLC methods from a physico-chemical point of
view are provided.
This book elucidates the role of HPLC throughout the entire drug
development process from drug candidate inception to marketed drug
product and gives detailed specifics of HPLC application in each
stage of drug development.
The latest advancements and trends in hyphenated and specialized
HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature
HPLC, high pressure liquid chromatography) are also discussed.
both novice and experienced pharmaceutical chemists who regularly
use HPLC as an analytical tool to solve challenging problems in the
pharmaceutical industry. It provides a unified approach to HPLC
with an equal and balanced treatment of the theory and practice of
HPLC in the pharmaceutical industry.
In-depth discussion of retention processes, modern HPLC
separation theory, properties of stationary phases and columns are
well blended with the practical aspects of fast and effective
method development and method validation. Practical and pragmatic
approaches and actual examples of effective development of
selective and rugged HPLC methods from a physico-chemical point of
view are provided.
This book elucidates the role of HPLC throughout the entire drug
development process from drug candidate inception to marketed drug
product and gives detailed specifics of HPLC application in each
stage of drug development.
The latest advancements and trends in hyphenated and specialized
HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature
HPLC, high pressure liquid chromatography) are also discussed.
Autoren-Porträt von Yuri V. Kazakevich, Rosario LoBrutto
Dr. YURI KAZAKEVICH is an Associate Professor of AnalyticalChemistry at Seton Hall University with thirty years of experience
in liquid chromatography. He has over fifteen years of academic
research experience in Russia and fifteen years of research,
teaching and consulting for major American pharmaceutical
companies, which has resulted in numerous papers and four book
chapters. The main focus of Dr. Kazakevich's research is in HPLC
retention mechanisms and the description of the analyte migration
through the column with an emphasis on the influence of adsorbent
geometry and surface chemistry. Dr. Kazakevich is the author of
Basic Liquid Chromatography, one of the oldest and most complete
online instructional resources on HPLC.
Dr. ROSARIO LOBRUTTO has over thirteen years of
experience in the pharmaceutical industry working both with drug
substances and drug products. He is a Group Head in the
Pharmaceutical and Analytical Development Department at Novartis
Pharmaceuticals Corporation managing multiple early to late phase
projects for both small drug molecules and proteins/peptides and is
responsible for teaching in-house HPLC method development training.
Dr. LoBrutto is the author of twenty research articles, fifty
presentations, and five book chapters in different areas of
analytical/physical chemistry and has served as an adjunct
professor for seven years. Dr. LoBrutto's main research directions
include HPLC retention mechanisms, the influence of mobile phase
modifiers on analyte retention and chromatographic figures of
merit, and method development strategies for small molecules and
proteins/peptides.
Bibliographische Angaben
- Autoren: Yuri V. Kazakevich , Rosario LoBrutto
- 2007, 1. Auflage, 1136 Seiten, Englisch
- Verlag: John Wiley & Sons
- ISBN-10: 0470087943
- ISBN-13: 9780470087947
- Erscheinungsdatum: 04.01.2007
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