Clinical Pharmacology and Therapeutics / Lecture Notes (ePub)

Contributors, iv Preface, vi Acknowledgements, vii Part 1 Principles of Clinical Pharmacology 1 Pharmacodynamics and pharmacokinetics, 3 2 Clinical trials and drug development, 12 Part 2 Aspects of Therapeutics 3 Drugs and gastrointestinal disease, 21 4 Management of coronary artery disease and its complications, 33 5 Primary and secondary prevention of cardiovascular disease, 58 6 Drugs used to treat respiratory disease, 78 7 Drugs used to treat neurological disease, 89 8 Treatment of psychiatric disorders, 108 9 Antimicrobial therapy, 124 10 HIV and antiretroviral treatment, 148 11 Travel medicine and tropical disease, 160 12 Drugs and endocrine disease, 171 13 Drugs and the reproductive system, 190 14 Drugs and the urological system, 199 15 Cancer therapeutics, 205 16 Immunopharmacology, 217 17 Corticosteroids, 225 18 Drugs and the blood including anticoagulants and thrombolytic drugs, 229 19 Drugs and inflammatory joint disease, 244 20 Anaesthesia and the relief of pain, 254 Part 3 Practical Aspects of Prescribing 21 Clinical pharmacokinetics: dosage individualisation, 267 22 Influence of renal and hepatic disease on pharmacokinetics and pharmacodynamics, 273 23 Prescribing at extremes of age, 278 24 Drugs in pregnant and breastfeeding women, 282 25 Pharmacoeconomics: the economic evaluation of new drugs, 290 26 Poisoning and drug overdose, 297 27 Drugs you may need in a hurry, 313 28 Prescribing and its pitfalls, 318 Index, 326

Gerard A. McKay: Consultant Physician and Honorary ClinicalSenior Lecturer, Glasgow Royal Infirmary

John L. Reid: Emeritus Professor of Medicine andTherapeutics, University of Glasgow

Matthew R. Walters: Professor of Clinical Pharmacologyand Honorary Consultant Physician, Division of Cardiovascular andMedical Sciences, University of Glasgow

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