Medicinal Chemistry of Nucleic Acids / Wiley series in drug discovery and development (PDF)

Complete, up-to-date coverage of the broad area of nucleic acid
chemistry and biology

Assembling contributions from a collection of authors with
expertise in all areas of nucleic acids, medicinal chemistry, and
therapeutic applications, Medicinal Chemistry of Nucleic
Acids presents a thorough overview of nucleic acid
chemistry--a rapidly evolving and highly challenging
discipline directly responsible for the development of antiviral
and antitumor drugs. This reliable resource delves into a multitude
of subject areas involving the study of nucleic acids--such as
the new advances in genome sequencing, and the processes for
creating RNA interference (RNAi) based drugs--to assist
pharmaceutical researchers in removing roadblocks that hinder their
ability to predict drug efficacy. Offering the latest cutting-edge
science in this growing field, Medicinal Chemistry of Nucleic Acids
includes:

* In-depth coverage of the development and application of modified
nucleosides and nucleotides in medicinal chemistry

* A close look at a large range of current topics on nucleic acid
chemistry and biology

* Essential information on the use of nucleic acid drugs to treat
diseases like cancer

* A thorough exploration of siRNA for RNAi and the regulation of
microRNA, non-coding RNA (ncRNA), a newly developing and exciting
research area

Thorough in its approach and promising in its message,
Medicinal Chemistry of Nucleic Acids probes the new domains
of pharmaceutical research--and exposes readers to a wealth of
new drug discovery opportunities emerging in the dynamic field of
nucleic acid chemistry.