Microwaves in Organic and Medicinal Chemistry / Methods and Principles in Medicinal Chemistry Bd.25 (PDF)
(Sprache: Englisch)
The authors of this guide are experts on the use of microwaves for drug synthesis as well as having much experience in teaching courses held under the auspices of the American Chemical Society and the IUPAC.
In this handy source of information for any...
In this handy source of information for any...
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The authors of this guide are experts on the use of microwaves for drug synthesis as well as having much experience in teaching courses held under the auspices of the American Chemical Society and the IUPAC.
In this handy source of information for any practicing synthetic chemist they focus on common reaction types in medicinal chemistry, including solid-phase and combinatorial methods. They consider the underlying theory, latest developments in microwave applications and include a variety of examples from recent literature, as well as less common applications that are equally relevant for organic and medicinal chemists.
An indispensable reference for researchers with an affinity to modern methods.
In this handy source of information for any practicing synthetic chemist they focus on common reaction types in medicinal chemistry, including solid-phase and combinatorial methods. They consider the underlying theory, latest developments in microwave applications and include a variety of examples from recent literature, as well as less common applications that are equally relevant for organic and medicinal chemists.
An indispensable reference for researchers with an affinity to modern methods.
Inhaltsverzeichnis zu „Microwaves in Organic and Medicinal Chemistry / Methods and Principles in Medicinal Chemistry Bd.25 (PDF)“
Introduction: Microwave Synthesis in Perspective MICROWAVE THEORY Microwave Radiation Microwave Dielectric Heating Microwave versus Conventional Thermal Heating Microwave Effects EQUIPMENT REVIEW Domestic Microwave Ovens Microwave Reactors for Organic Synthesis Multimode Instruments Single-Mode Instruments MICROWAVE PROCESSING TECNIQUES Solvent-free Reactions Phase-Transfer Catalysis Reactions Using Solvents Parallel Processing Scale-Up in Batch and Continuous Flow GETTING STARTED WITH MICROWAVE CHEMISTRY Why Use Microwave Reactors? Translating Convenionally Heated Methods Reaction Optimization and Library Generation Limitations and Safety Aspects LITERATURE SURVEY: GENERAL ORGANIC SYNTHESIS Transition Metal-catalyzed Carbon-Carbon Bond Formation Transition Metal-catalyzed Carbon-Heteroatom Bond Formation Other Transition Metal-mediated Processes Heterocycle Synthesis LITERATURE SURVEY: COMBINATORIAL AND HIGH-THROUGHPUT SYNTHESIS Solid-Phase Organic Synthesis Soluble Polymer-supported Synthesis Task-specific Ionic Liquids Fluorous Synthesis Polymer-supported Reagents, Catalysts and Scavengers
Autoren-Porträt von C. Oliver Kappe, Alexander Stadler
C. Oliver Kappe was born in Graz (Austria) and received his doctoral degree from the Karl-Franzens-University in Graz in 1992, working with Gert Kollenz on acylketenes. After postdoctoral research work with Curt Wentrup at the University of Queensland, Brisbane (Australia), and with Albert Padwa at Emory University, Atlanta (USA), he moved back to the University of Graz where he currently holds a position as associate Professor. In 2003 he spent a sabbatical at the Scripps Research Institute in La Jolla (USA) with K. Barry Sharpless. His research focuses on microwave-enhanced synthesis, combinatorial chemistry, multicomponent reactions, and biologically active heterocycles.Alexander Stadler was born in Bruck and der Mur (Austria) and studied Chemistry at the University of Graz. He then obtained his doctoral degree for studies on microwave-accelerated reactions in solution and on solid phase in the group of C. Oliver Kappe. After postdoctoral research work on microwave-assisted transition metal-catalyzed coupling reactions in the group of Mats Larhed at the University of Uppsala (Sweden) he joined Anton Paar GmbH in Graz in 2004 as product specialist for microwave synthesis.
Bibliographische Angaben
- Autoren: C. Oliver Kappe , Alexander Stadler
- 2006, 1. Auflage, 410 Seiten, Englisch
- Verlag: Wiley-VCH Verlag GmbH & Co. KGaA
- ISBN-10: 3527606831
- ISBN-13: 9783527606832
- Erscheinungsdatum: 12.05.2006
Abhängig von Bildschirmgröße und eingestellter Schriftgröße kann die Seitenzahl auf Ihrem Lesegerät variieren.
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