Molecular Basis of Oxidative Stress (PDF)

Sets the stage for the development of better diagnostic
techniques and therapeutics

Featuring contributions from an international team of leading
clinicians and biomedical researchers, Molecular Basis of
Oxidative Stress reviews the molecular and chemical bases of
oxidative stress, describing how oxidative stress can lead to the
development of cancer and cardiovascular and neurodegenerative
diseases. Moreover, it explains the potential role of free radicals
in both the diagnosis and the development of therapeutics to treat
disease.

Molecular Basis of Oxidative Stress is logically
organized, beginning with a comprehensive discussion of the
fundamental chemistry of reactive species. Next, the book:

* Presents new mechanistic insights into how oxidative damage of
biomolecules occurs

* Examines how these oxidative events effect cellular
metabolism

* Investigates the role of oxidative stress in the pathogenesis
of cancer, neurodegenerative disease, cardiovascular disease, and
cystic fibrosis

* Explores opportunities to improve the diagnosis of disease and
the design of new therapeutic agents

Readers will find much novel information, including new radical
chemistries and the latest discoveries of how free radicals react
with biomolecules. The contributors also present recent findings
that help us better understand the initiation of oxidative stress
and the mechanisms leading to the pathogenesis of various
diseases.

Throughout the book, the use of molecular structures helps
readers better understand redox chemistry. In addition, plenty of
detailed figures illustrate the mechanisms of oxidative stress and
disease pathogenesis.

Examining everything from the basic chemistry of oxidative
stress to the pathogenesis of disease, Molecular Basis of
Oxidative Stress will help readers continue to explore the
nature of oxidative stress and then use that knowledge to develop
new approaches to prevent, detect, and treat a broad range of
disease conditions.