Multi-dimensional Vibrational Circular Dichroism (PDF)
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This book provides the reader with the latest research on vibrational circular dichroism (VCD) spectroscopy including its useful features and applications to many fields. The book starts from an unresolved question in gel chemistry of how component molecules are organized in the flexible fibrils of gels. VCD spectroscopy was successful in giving a clear answer to this mystery. The book also describes a key aspect of this technique lay in the fact that VCD signals were remarkably enhanced when chiral molecules formed a stereoregular molecular array over a few hundred nanometers. VCD spectroscopy was also applied to other topics involving chiral molecules such as the chiral discrimination mechanism in heterogeneous asymmetric catalysis and the build-up of supramolecular chirality in molecular crystals. Furthermore, the book covers the recent instrument developments leading to multi-dimensional VCD measurements with the coordinates of wavenumber, space and time. This progress has opened up new biological and medical applications such as the heterogenous distributions of protein domains in insect wings and the quality control of chiral drugs. The last part of the book presents the possibility of medical diagnosis of Alzheimer's disease through multi-dimensional VCD analyses.
This book appeals not only to researchers and students who study spectroscopy but also to ones in catalysis, biology and medicine as users of the VCD methods.
Jun Yoshida received the Dr. Sci. degree from the University of Tokyo in 2009.After working at Kao Corporation, he joined Kitasato University as an assistant professor and later as a lecturer. During 2014-2015, he stayed at Simon Fraser University as a visiting researcher. In 2021, he moved to Nihon University as an associate professor. His current interest is the development of helical supramolecules and understanding the inner structure.
Akihiko Yamagishi received the Dr. Sci. degree from the University of Tokyo, Tokyo, Japan, in 1975. He was a professor in the Graduate School of Science at the University of Tokyo during 2001-2005. He is a visiting researcher in the Department of Medicine at Toho University. He received the Award for Creative Work from the Chemical Society of Japan in 1986, the Award from the Clay Mineral Society of Japan in 1999 and the Marilyn and Sturges W. Bailey Distinguished Member Award from the American Clay Mineral Society in 2012. He is a fellow of the Chemical Society of Japan.
- Autoren: Hisako Sato , Jun Yoshida , Akihiko Yamagishi
- 2024, 2024, 209 Seiten, Englisch
- Verlag: Springer Nature Singapore
- ISBN-10: 9819703913
- ISBN-13: 9789819703913
- Erscheinungsdatum: 29.03.2024
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- Größe: 9.13 MB
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