New Frontiers in Asymmetric Catalysis (PDF)

A compilation of recent advances and applications in asymmetric
catalysis

The field of asymmetric catalysis has grown rapidly and plays a key
role in drug discovery and pharmaceuticals. New Frontiers in
Asymmetric Catalysis gives readers a fundamental understanding of
the concepts and applications of asymmetric catalysis reactions and
discusses the latest developments and findings. With contributions
from preeminent scientists in their respective fields, it
covers:

* "Rational" ligand design, which is critically dependent on the
reaction type (reduction, oxidation, and C-C bond formation)

* Recent findings on activation of C-H bonds, C-C bonds, and small
molecules (C=O, HCN, RN=C, and CO2) and the latest developments on
C-C bond reorganization, such as metathesis

* Advances in "chirally economical" non-linear phenomena, racemic
catalysis, and autocatalysis

* Some of the recent discoveries that have led to a renaissance in
the field of organocatalysis, including the development of chiral
Brönstead acids and Lewis acidic metals bearing the conjugate
base of the Brönstead acids as the ligands and the chiral
bi-functional acid/base catalysts

The book ends with a thought-provoking perspective on the future of
asymmetric catalysis that addresses both the challenges and the
unlimited potential in this burgeoning field. This is an
authoritative, up-to-date reference for organic chemists in
academia, government, and industries, including pharmaceuticals,
biotech, fine chemicals, polymers, and agriculture. It is also an
excellent textbook for graduate students studying advanced organic
chemistry or chemical synthesis.