Omics Approaches to Understanding Muscle Biology / Methods in Physiology (PDF)
48 DeutschlandCard Punkte sammeln
- Lastschrift, Kreditkarte, Paypal, Rechnung
- Kostenloser tolino webreader
This book is a collection of principles and current practices in omics research, applied to skeletal muscle physiology and disorders. The various sections are categorized according to the level of biological organization, namely, genomics (DNA), transcriptomics (RNA), proteomics (protein), and metabolomics (metabolite). With skeletal muscle as the unifying theme, and featuring contributions from leading experts in this traditional field of research, it highlights the importance of skeletal muscle tissue in human development, health and successful ageing. It also discusses other fascinating topics like developmental biology, muscular dystrophies, exercise, insulin resistance and atrophy due to disuse, ageing or other muscle diseases, conveying the vast opportunities for generating new hypotheses as well as testing existing hypotheses by combining high-throughput techniques with proper experiment designs, bioinformatics and statistical analyses.
Presenting the latest research techniques, this book is a valuable resource for the physiology community, particularly researchers and grad students who want to explore the new opportunities for omics technologies in basic physiology research.
Yi-Wen Chen is an Associate Professor of Genomics and Precision Medicine at the George Washington University and Principal Investigator at the Center for Genetic Medicine Research, Children's National Health System, DC, USA. Her research uses transcriptomic approaches to study molecular pathways in muscles in response to physiological stimuli and pathological conditions. Yi-Wen uses genome-wide RNA profiling to dissect the disease mechanisms of various muscle disorders and to identify molecular mechanisms of adaptive remodelling. In addition, her group uses next-generation sequencing and long-read sequencing to study genetic, epigenetic and transcriptomic changes in muscles using physiological and disease models. Currently she is part of the Human Cell Atlas consortium, with a focus on single-cell profiles and spatial characterization of gene expression in skeletal muscles at different
- 2019, 1st ed. 2019, 217 Seiten, Englisch
- Herausgegeben: Jatin George Burniston, Yi-Wen Chen
- Verlag: Springer-Verlag GmbH
- ISBN-10: 1493998021
- ISBN-13: 9781493998029
- Erscheinungsdatum: 05.11.2019
Abhängig von Bildschirmgröße und eingestellter Schriftgröße kann die Seitenzahl auf Ihrem Lesegerät variieren.
- Dateiformat: PDF
- Größe: 6.25 MB
- Ohne Kopierschutz
- Vorlesefunktion
Zustand | Preis | Porto | Zahlung | Verkäufer | Rating |
---|
Schreiben Sie einen Kommentar zu "Omics Approaches to Understanding Muscle Biology / Methods in Physiology".
Kommentar verfassen