Oral Bioavailability / Wiley series in drug discovery and development (ePub)
Basic Principles, Advanced Concepts, and Applications
(Sprache: Englisch)
Understand and assess the design, delivery, and efficacy of
orally administered drugs
A practical guide to understanding oral bioavailability, one of
the major hurdles in drug development and delivery, Oral
Bioavailability: Basic Principles, Advanced...
orally administered drugs
A practical guide to understanding oral bioavailability, one of
the major hurdles in drug development and delivery, Oral
Bioavailability: Basic Principles, Advanced...
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Understand and assess the design, delivery, and efficacy of
orally administered drugs
A practical guide to understanding oral bioavailability, one of
the major hurdles in drug development and delivery, Oral
Bioavailability: Basic Principles, Advanced Concepts, and
Applications is designed to help chemists, biologists, life science
researchers, pharmaceutical scientists, pharmacologists,
clinicians, and graduate and students become familiar with the
fundamentals and practices of the science of oral
bioavailability.
The difference in rate and extent between a drug taken orally
and the actual amount of a drug reaching the circulatory system,
oral bioavailability is an essential parameter for determining the
efficacy and adverse effects of new and developing medications, as
well as finding an optimal dosing regimen.
This book provides a much-needed one-stop resource to help
readers better understand and appreciate the many facets and
complex problems of oral bioavailability, including the basic
barriers to oral bioavailability, the methods used to determine
relevant parameters, and the challenges of drug delivery.
In addition, this comprehensive book discusses biological and
physicochemical methods for improving bioavailability, integrates
physicochemistry with physiology and molecular biology, and
includes several state-of-the-art technologies and
approaches--Caco-2 cell culture model, MDCK, and other related
cell culture models--which are used to study the science of
oral bioavailability.
orally administered drugs
A practical guide to understanding oral bioavailability, one of
the major hurdles in drug development and delivery, Oral
Bioavailability: Basic Principles, Advanced Concepts, and
Applications is designed to help chemists, biologists, life science
researchers, pharmaceutical scientists, pharmacologists,
clinicians, and graduate and students become familiar with the
fundamentals and practices of the science of oral
bioavailability.
The difference in rate and extent between a drug taken orally
and the actual amount of a drug reaching the circulatory system,
oral bioavailability is an essential parameter for determining the
efficacy and adverse effects of new and developing medications, as
well as finding an optimal dosing regimen.
This book provides a much-needed one-stop resource to help
readers better understand and appreciate the many facets and
complex problems of oral bioavailability, including the basic
barriers to oral bioavailability, the methods used to determine
relevant parameters, and the challenges of drug delivery.
In addition, this comprehensive book discusses biological and
physicochemical methods for improving bioavailability, integrates
physicochemistry with physiology and molecular biology, and
includes several state-of-the-art technologies and
approaches--Caco-2 cell culture model, MDCK, and other related
cell culture models--which are used to study the science of
oral bioavailability.
Autoren-Porträt von Xiaoling Li
Ming Hu, PhD, is Professor of Pharmaceutics at the College of Pharmacy, University of Houston. Dr. Hu is on the editorial boards of Molecular Pharmaceutics and the Journal of Alternative and Complementary Medicine.Xiaoling Li, PhD, is Professor of Pharmaceutics and Associate Dean of Graduate Education and Research at the Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific. He is a Fellow of the American Association of Pharmaceutical Scientists.
Bibliographische Angaben
- Autor: Xiaoling Li
- 2011, 1. Auflage, 560 Seiten, Englisch
- Herausgegeben: Ming Hu
- Verlag: John Wiley & Sons
- ISBN-10: 1118067584
- ISBN-13: 9781118067581
- Erscheinungsdatum: 04.08.2011
Abhängig von Bildschirmgröße und eingestellter Schriftgröße kann die Seitenzahl auf Ihrem Lesegerät variieren.
eBook Informationen
- Dateiformat: ePub
- Größe: 25 MB
- Mit Kopierschutz
Sprache:
Englisch
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