Protein Degradation (PDF)
Vol. 3: Cell Biology of the Ubiquitin-Proteasome System
(Sprache: Englisch)
The third of four volumes discusses the role of ubiquitin-mediated protein breakdown in cellular regulation and physiology. Required reading for molecular biologists, cell biologists and physiologists with an interest in the topic.
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The third of four volumes discusses the role of ubiquitin-mediated protein breakdown in cellular regulation and physiology. Required reading for molecular biologists, cell biologists and physiologists with an interest in the topic.
Inhaltsverzeichnis zu „Protein Degradation (PDF)“
Ubiquitin: a new player in the peroxisome field The ubiquitin-proteasome system and muscle development The COP9 signalosome: structural and biochemical conservation and its roles in the regulation of plant development Ubiquitin and protein sorting to the lysosome ISG15-Dependent Regulation The role of the ubiquitin proteasome pathway in the regulation of the cellular hypoxia response p97 and ubiquitin: A complex story Cdc48 (p97) and its co-factors Deubiquitylating enzymes, cell proliferation, and cancer
Autoren-Porträt
John Mayer obtained his MS and PhD degrees from the University of Birmingham (UK). He is currently serving as Professor of Biochemistry at the School of Biomedical Sciences at Nottingham University.For the past 30 years, he has investigated intracellular proteolysis and particularly the ubiquitin/proteasome system. Presently, he is particularly interested in intracellular proteolysis in relation to neurodegenerative illnesses.
Aaron Ciechanover obtained his MD from the Hebrew University in Jerusalem (Israel), and his PhD from the Technion-Israel Institute of Technology in Haifa, where he is presently serving as Professor of Biochemistry. Professor Ciechanover is known for his discovery of the first ubiquitin system mutant cell, demonstrating the role of the ubiquitin-proteasome proteolytic system in protein degradation in vivo. In 2004, he has received the Nobel Prize in Chemistry for his ground-breaking work on the ubiquitin-proteasome system.
Martin Rechsteiner is Professor of Biochemistry at the University of Utah in Salt Lake City (USA). He is interested in the proteasome component of the ubiquitin-proteasome pathway. He has identified several key regulators of proteasome function and is currently working on their structural and functional elucidation.
Bibliographische Angaben
- 2008, 1. Auflage, 238 Seiten, Englisch
- Herausgegeben: R. John Mayer, Aaron J. Ciechanover, Martin Rechsteiner
- Verlag: Wiley-VCH
- ISBN-10: 352762029X
- ISBN-13: 9783527620296
- Erscheinungsdatum: 25.06.2008
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- Größe: 6.72 MB
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Englisch
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